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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.