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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Finasteride helps female-pattern hair loss.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Alzheimer's patients have higher levels of certain chemicals in their hair.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

Zinc is essential for many body functions and imbalances can lead to health problems.

Zinc made mice's coarse hair turn into fine hair without affecting skin structure.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

Gene mutations can cause problems in male genital development.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Oestrogens are key for bone growth during puberty in both boys and girls.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

New treatments for male hypogonadism are effective and should be personalized.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Minoxidil reduces lysine hydroxylase in skin cells.

Combination therapy improves hair growth in advanced hair loss.