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The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.

Androgens can both increase and decrease hair growth in different parts of the body.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

Healthcare providers should start with simple fertility tests and treatments before referring patients to specialists.

A boy with progeria had eye problems and signs of aging like hair loss and skin wrinkling.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Gene mutations can cause problems in male genital development.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

CDP is crucial for lung and hair follicle cell development.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

Consider benefits and risks of new alopecia treatments for safety.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.