January 2025 in “Ginekologia Polska” In this study, researchers found that certain vitamin D receptor gene polymorphisms are significantly related to insulin concentration during a glucose tolerance test in young women with hyperandrogenism, but these polymorphisms did not affect bone metabolism or other biochemical parameters.
January 2025 in “International Journal of Gynaecology Research” This study found that serum cystatin C levels may be elevated in adolescent females with PCOS, suggesting it could serve as a predictive marker for metabolic and cardiovascular issues independent of renal function.
In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.
This study identified 193 plasma proteins associated with prostate cancer risk, validating 20 high-risk proteins including KLK3, and pinpointed potential drug targets like HSPB1, RRM2B, and PSCA through genetic analysis, offering new insights for biomarkers and treatments.
August 2024 in “Frontiers in Pharmacology” This review discusses the potential of therapeutic antibodies as an alternative treatment for androgenetic alopecia, highlighting the initial development stages and the need for further validation and optimization of targets like the prolactin receptor and Interleukin-6 receptor.
January 2024 in “Regenerative Biomaterials” This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.
December 2023 in “Biointerface Research in Applied Chemistry” This study used molecular docking to identify stiripentol as a potential new inhibitor of the SRD5A2 enzyme, which is targeted for treating androgen-related diseases; however, in vivo trials are needed to validate its efficacy.
In this report, a 51-year-old woman with systemic lupus erythematosus presented with recurrent joint pain and irregular patches of hair loss, raising differential diagnoses of androgenetic alopecia, lupus-related alopecia, or seborrheic dermatitis.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reports that a low concentration of chitosan induces callose deposition and slows root hair growth in Arabidopsis, suggesting an evolutionary conservation of this response to mild biotic stress across plant types.
This case report details a 38-year-old woman in Sri Lanka diagnosed with systemic lupus erythematosus-associated protein-losing enteropathy, identified through hypoalbuminemia and EULAR criteria in a resource-limited setting.
November 2022 in “Journal of the Endocrine Society” In this case study, biotin supplementation was reported to interfere with free testosterone assay results, leading to falsely low readings in a postmenopausal woman with hyperandrogenism.
January 2022 in “The Egyptian Journal of Hospital Medicine” This study found that higher serum IL-21 levels may serve as a promising diagnostic and prognostic marker for alopecia areata, strongly correlating with disease activity.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This research found that the microtubule catastrophe factor KIF18B plays a crucial role in promoting spindle orientation in keratinocytes, linking this process to cell fate decisions during hair follicle morphogenesis.
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reports that structural and biochemical analysis of steroid 5α-reductases clarifies how they mediate steroid reduction with NADPH, potentially aiding in designing targeted therapies.
September 2019 in “Philippine Journal of Internal Medicine” This study found that Filipino patients with lupus typically develop myocarditis early and respond well to early immunosuppressive therapy.
May 2019 in “Cytotherapy” This study explored how Australian patients and their carers perceived autologous stem cell interventions, highlighting factors like illness experience and unrealistic expectations that influenced their decision-making in an unregulated market.
April 2019 in “Dermatology reports” This case study reported that scalp dermoscopy, or trichoscopy, provided a useful noninvasive method to evaluate and confirm hair regrowth in a child treated for tinea capitis.
January 2019 in “Springer eBooks” Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
May 2018 in “International Journal of Advances in Medicine” This study reports the successful management of acute liver failure in a 25-year-old woman with concurrent Hepatitis B and autoimmune hepatitis, using a combination of steroids, azathioprine, and tenofovir disoproxil fumarate.
August 2017 in “Journal of evolution of medical and dental sciences” In this study, researchers evaluated trichoscopy in diagnosing non-scarring alopecia and found diagnostic value in observing diverse hair diameters in androgenetic alopecia, black dots and broken hairs in alopecia areata, and empty follicles in telogen effluvium, supporting trichoscopy's utility in differentiating alopecia types.
April 2016 in “Plastic and reconstructive surgery. Global open” This article from the PRS Global Open and ASPS Education Network does not present any new research findings; it likely serves as an introductory or descriptive overview.
November 2013 in “Dermatologic Clinics” The document summarizes the latest trends and advancements in cosmetic dermatology.
January 2012 in “Journal of Investigative Dermatology” Some Greek melanoma patients have gene mutations linked to increased cancer risk, a new color feature helps diagnose melanoma, the incidence of a skin condition in the Netherlands is rare, and a gene possibly affects male-pattern baldness.
May 2006 in “Frontiers in Neuroendocrinology” This study found that patients with androgenic alopecia had altered neuroactive steroid levels and depression symptoms after stopping finasteride treatment, suggesting lingering neuropsychiatric effects.
May 1995 in “Journal of Investigative Dermatology” Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.
July 1980 in “International Journal of Dermatology” This article about Aloe Vera does not include any new research findings or results.
June 1930 in “Archives of dermatology” This case report describes a 26-year-old woman with chronic lupus erythematosus who did not improve after receiving eighty doses of gold and sodium thiosulphate.
April 2018 in “Journal of Chromatographic Science” In this study, researchers found that finasteride undergoes second-order alkaline degradation kinetics and that its degraded form negatively impacts cell proliferation, highlighting the need for careful handling in pharmaceutical manufacturing and storage.
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
March 1998 in “Journal of Dermatological Science” Combining RU58841 and minoxidil significantly increases hair growth.