10 citations
,
March 2014 in “Scandinavian journal of clinical and laboratory investigation” This study found that MDA-modified DNA may contribute to immune responses in alopecia areata patients by creating neo-epitopes, providing new insights into the condition's immunological mechanisms.
10 citations
,
April 2013 in “Journal of Investigative Dermatology” This study found that ovine dermal papilla cells exhibit robust aggregation in culture, offering a model to investigate the regulation of hair follicle dermal papilla size.
10 citations
,
January 2013 in “International Journal of Trichology” This study suggests that the presence of more than six vellus hairs in the frontal scalp at 20-fold magnification can be an additional criterion for diagnosing early female pattern hair loss.
9 citations
,
January 2021 in “Strahlentherapie und Onkologie” This case report suggests that topical St. John's wort oil may cause severe skin toxicity during radiotherapy for non-small cell lung cancer, acting as a significant radiosensitizer.
9 citations
,
December 2020 in “British Journal of Dermatology” This research letter reports that low-dose oral minoxidil improved hair density and length in children with loose anagen hair syndrome.
9 citations
,
October 2018 in “Elsevier eBooks” This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.
9 citations
,
February 2005 in “The Journal of Men's Health & Gender” This article reviews treatment options for male androgenetic alopecia, including their distinct aims of arresting progression, stimulating regrowth, and concealing hair loss, and reports no new clinical results.
8 citations
,
June 2024 in “APOPTOSIS” In this review, researchers discussed recent insights into caspases, enzymes initially associated with cell death and inflammation, revealing their broader roles in cell proliferation, migration, and differentiation, and highlighting the importance of caspase knock-out mice for understanding their implications in diseases.
8 citations
,
May 2022 in “International journal of nanomedicine” This study developed a fully natural resveratrol nanoparticle system using lecithin, showing potent anti-cancer activity in vitro and increased tumoral uptake in vivo on breast cancer models.
8 citations
,
July 2018 in “Analytical sciences” This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.
8 citations
,
May 2018 in “Primary Care: Clinics in Office Practice” This review details common symptoms of rheumatic diseases and how to differentiate them from other conditions based on patient history and physical examination.
8 citations
,
October 2016 in “Experimental dermatology” This paper proposes that the induction of HF-specific neo-antigens by peripheral CD8+ T cells may maintain self-tolerance but could also lead to immunopathology in conditions like alopecia areata.
7 citations
,
January 1998 in “EXPERIMENTAL ANIMALS” This study found no significant differences in lectinhistochemical characteristics of the dorsal skin epidermis between hypotrichotic WBN/Ila-Ht rats and Wistar rats, except for varying lectin binding intensity.
6 citations
,
January 2024 in “ACS Medicinal Chemistry Letters” This study found that the alkaloids cepharanthine and berbamine bind to SK2 and SK3 channel subtypes with affinities that match their concentrations active against various diseases, prompting further investigation into SK channels' role in their therapeutic effects.
6 citations
,
January 2015 in “Dermatology” This review covers trichoscopy's role in diagnosing scalp disorders, emphasizing its potential to improve clinical accuracy, but it reports no new clinical results.
6 citations
,
October 1993 in “Endocrinology” In this study, researchers found that finasteride inhibits progesterone synthesis by blocking cholesterol side-chain cleavage in mouse-derived MA-10 Leydig cells, but this effect may not be evident in human or rat cells.
6 citations
,
July 1990 in “The Journal of Pediatrics” A boy with toxic shock syndrome had severe heart rhythm problems but recovered with treatment.
6 citations
,
November 1980 in “Clinical Endocrinology” This study measured plasma testosterone glucosiduronate levels and found no overlap in those with hyperandrogenism compared to normal females, despite normal testosterone and dihydrotestosterone levels in half of the affected patients.
5 citations
,
November 2017 in “Dermatologica Sinica” In this study, transverse sectioning of scalp biopsy samples showed higher diagnostic accuracy than vertical sectioning for noncicatricial alopecia, although both techniques are important for accurate diagnosis.
5 citations
,
February 2014 in “Journal of Liquid Chromatography & Related Technologies” This study successfully developed and validated a reverse-phase HPLC method for accurately determining finasteride and tamsulosin simultaneously in bulk and pharmaceutical formulations.
4 citations
,
August 2010 in “Acta Biologica Hungarica” This study found that novel compounds moderately inhibited 5α-reductase type 1 activity compared to finasteride, offering valuable data on structure-activity relationships.
4 citations
,
January 2007 in “Sen'i Gakkaishi” This study found that permanent wave treatment accelerates hair degradation after protease exposure, showing significant morphological differences compared to untreated hair and linked to damage from Alpha-helical region denaturation.
3 citations
,
February 2022 in “Frontiers in cell and developmental biology” This study found that the circular RNA circCOL1A1 influences the formation of superior-quality brush hair in white goats by regulating hair follicle stem cell behavior and interacting with the miR-149-5p/CMTM3/AR axis.
3 citations
,
May 2018 in “Journal of Cosmetic Dermatology” This study reported that the most reliable way to differentiate alopecia areata from androgenic alopecia is by detecting intrafollicular CD3 and CD8 cell density, with CD3 being the most specific and sensitive marker.
3 citations
,
November 2014 in “Protein Expression and Purification” This study reported successful recovery of biologically active recombinant murine Wnt3a without detergent, suggesting usefulness for structure-activity studies avoiding detergent-related issues.
3 citations
,
February 2009 in “Chinese Journal of Traumatology (english Edition)” This study found that implanting microencapsulated dermal papilla cells in rat ears led to hair follicle regeneration, suggesting a potential alternative to fresh isolated dermal papillae for inducing hair growth.
3 citations
,
April 1989 in “Drug Information Journal” Side effects of drugs can lead to the discovery of new treatments.
2 citations
,
November 2019 in “Cancer reports” This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.
2 citations
,
October 2019 in “Current sports medicine reports” This case report describes a high school wrestler whose forearm rash was initially misdiagnosed as eczema, later identified as Majocchi's granuloma, and successfully treated with oral antifungal therapy after a biopsy.
2 citations
,
September 2018 in “Journal of Separation Science” This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.