37 citations
,
June 2018 in “Clinical and Experimental Medicine” This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.
36 citations
,
June 2018 in “Journal of Dermatology” This article updates Japanese guidelines for diagnosing and treating male and female-pattern hair loss, recommending specific drugs and therapies while advising against certain treatments for female-pattern hair loss.
36 citations
,
August 2011 in “Journal of Controlled Release” This review explores the potential of using genetically-manipulated stem cells as both therapeutic agents and gene delivery vehicles for enhanced wound regeneration, but it reports no new clinical results.
35 citations
,
May 2021 in “Nature communications” This study found that basement membrane components and structures in mouse hair follicles are highly specialized for specific inter-tissue interactions, with laminin α5 playing a crucial role in hair cycle regulation and anchoring.
35 citations
,
July 2015 in “Journal of Affective Disorders” This study found that women with polycystic ovary syndrome have significantly higher scores for affective temperaments and anxiety and depression than healthy controls, suggesting risk for depressive and anxiety disorders.
35 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that intralesional triamcinolone acetonide is effective for treating localized patchy alopecia areata, with dermoscopy aiding in early detection of clinical response and adverse effects.
34 citations
,
May 2017 in “Lasers in Surgery and Medicine” This study found that combining low-level light therapy with topical minoxidil 5% may lead to better hair regrowth and patient satisfaction in treating female pattern hair loss compared to using each treatment alone.
34 citations
,
February 2016 in “Fertility and Sterility” This study suggests that higher PDCD4 expression may play a significant role in polycystic ovary syndrome pathogenesis through its association with obesity, insulin resistance, lipid metabolism disorders, and increased granulosa cell apoptosis.
34 citations
,
April 2014 in “Psychopharmacology” This review discusses the pharmacological properties and physiological regulation of neuroactive steroids, focusing on their varied responses to stress and ethanol in rats, mice, and humans, but it reports no new findings.
34 citations
,
March 2003 in “Veterinary Dermatology” This study found that in dogs with alopecia, certain steroid hormone levels were elevated, particularly progesterone, but not all hormone abnormalities were consistent across breeds, suggesting the need for breed-specific evaluation.
33 citations
,
September 2014 in “Reproductive Biology and Endocrinology” In this study, elevated afamin concentrations were associated with metabolic syndrome in young women, particularly those with insulin resistance, suggesting a potential predictive role for afamin in metabolic risk assessment.
33 citations
,
October 2004 in “Archives of Dermatological Research” This study suggests that a larger prostate is associated with a higher prevalence of androgenetic alopecia, although the prostate size did not correlate with alopecia severity.
32 citations
,
November 2018 in “Anais Brasileiros de Dermatologia” This study highlighted the importance of aesthetic and common dermatological conditions such as acne and nonmelanoma skin cancer in Brazil, with varying patterns based on demographic and funding factors.
32 citations
,
February 2008 in “Journal of the American Academy of Dermatology” This case report describes a family with autosomal dominant transmission of keratosis follicularis spinulosa decalvans, with observed treatment refractoriness in multiple topical and systemic therapies.
32 citations
,
April 2006 in “The Journal of Urology” Using finasteride with TIP extends time off period for prostate cancer patients.
31 citations
,
February 2014 in “Inflammation Research” This study found that reduced expression of CD200R1 on monocyte-derived macrophages in rheumatoid arthritis patients was significantly associated with higher disease severity and an imbalance in Th17/Treg cells.
31 citations
,
November 2000 in “Clinical and Experimental Dermatology” This study developed the Women's Androgenetic Alopecia Quality of Life Questionnaire, which shows high reliability and internal consistency for assessing the impact of AGA on women's quality of life.
31 citations
,
January 1981 in “Pharmacology & Therapeutics” In this study, 13-cis-5S*,8S*-epidioxy-5,8-dihydroretinoic acid was found to be significantly more cytotoxic to cancer cell lines than other retinoic acid analogs evaluated.
30 citations
,
January 2019 in “Clinical Endocrinology” This study observed that serum AMH concentration and LH/FSH ratio showed comparable diagnostic value for PCOS among infertile women, though neither is adequate alone for diagnosis.
30 citations
,
May 2016 in “International Journal of Cosmetic Science” This study found that apoptosis was more prevalent in hair follicles of women with female pattern hair loss, particularly in miniaturized follicles, and was associated with follicular inflammation.
30 citations
,
March 2015 in “Journal of Dermatology” This study found that certain trichoscopic features like white peripilar sign, yellow dots, and scalp pigmentation are positively correlated with the severity of androgenetic alopecia in Chinese patients.
30 citations
,
June 1988 in “Journal of Steroid Biochemistry” This study found that combining Flutamide and an LHRH agonist in adult male rats effectively inhibited prostatic growth and reduced androgen-sensitive prostatic activity markers to levels similar to castrated rats.
29 citations
,
March 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that the severity, duration, and relapse rate of alopecia areata decreased with older age at onset, while relapses mostly occurred early and declined over time.
29 citations
,
January 2009 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome have significantly higher plasma levels of thrombin-activatable fibrinolysis inhibitor and other hemostatic markers compared to age- and BMI-matched healthy controls.
29 citations
,
June 2005 in “Journal of Zoo and Wildlife Medicine” This study concluded that coat damage in captive rhesus macaques is unlikely caused by parasitic, bacterial, or mycotic infections but may be linked to environmental or behavioral factors affecting hair growth.
28 citations
,
July 2015 in “American Journal of Clinical Dermatology” This study found a higher prevalence of metabolic syndrome in patients with lichen planus, especially those with mucosal involvement, which is associated with increased cardiovascular and diabetes risk.
28 citations
,
April 2014 in “Hormones” This study found that increased serum A4A levels were associated with more severe polycystic ovary syndrome phenotypes and could be a useful marker for biochemical hyperandrogenemia.
28 citations
,
November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study indicates that the normal human prostate is not a major contributor to circulating blood DHT concentrations in androgen-deficient patients receiving testosterone replacement therapy.
27 citations
,
January 2020 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This abstract outlines a questionnaire study conducted among doctors and nurses in Turkey during the early days of the COVID-19 outbreak, but it provides no new results.
27 citations
,
March 2018 in “Biomaterials” This study found that a cocktail of three proteins from embryonic skin can enable adult fibroblasts to regenerate hair follicles by altering gene expression and activating regenerative signaling pathways.