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In this study, TASP0382088 showed potent selective inhibition of the ALK5 receptor, significantly reducing Smad2 phosphorylation in mouse skin following topical application.

This study found that combining MSM with MAP significantly enhanced hair growth in mice, comparable to or better than minoxidil, due to increased intradermal retention of MAP.

This study found that Si Jun Zi Tang may have anti-aging effects in mice, linked to inhibition of the PI3K-AKT and P38 MAPK signaling pathways.

This study found that short durations of heat and specific chemical penetration enhancers significantly improved the delivery of finasteride to human scalp skin and hair follicles.

This study provides a detailed profile of bioactive polyphenols in various parts of the baobab fruit, highlighting its potential as a health-promoting food or supplement.

This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.

This study found that a high sesquiterpene C. aeruginosa extract significantly reduced axillary hair growth in women compared to placebo with no apparent adverse effects.

This study optimized and validated a dissolution test method for immediate-release finasteride capsules, highlighting the need for an official standard due to variability in commercial products.

This study described a potentiometric titration method for determining minoxidil, which showed recoveries of 97.4 to 98.7% and agreed with chromatographic results within a 90% confidence level.

This study found that mature leaves of Japanese 'Saijo' persimmon have the highest ascorbic acid levels, whereas polyphenol levels were high in both mature leaves and adventitious shoots but low in young shoots.

In this study, EPC-K, a compound with antioxidant and moisturizing effects, was found to decompose significantly under certain conditions, impacting its stability in quasi drug hair-growing products.

This study found that cocaine disrupted the relationship between certain brain androgen levels and sexual behavior in male rats, with dose-dependent effects on testosterone metabolism.

This study reported that polyamine levels, especially N-acetyl polyamines, were higher in the vertex region of the scalp than in the occipital region in patients with male and female pattern hair loss.

In this study, tresses treated with pH 1.0 acid straightener showed better straightening but more damage to hair properties compared to those treated with pH 2.0.

This study developed and validated an RP-HPLC-PDA method for accurately estimating Tamsulosin and Finasteride in bulk and tablet forms, achieving precise detection and linearity within specified concentration ranges.

Terbinafine can cause hair loss.

This study found that oregonin, isolated from Alnus japonica, demonstrated strong antioxidant activity and apoptosis modulation in hair follicle cells, suggesting its potential as a natural ingredient for preventing hair loss in cosmetic products.

This study identified two new Wnt genes, EsWnt1 and EsWnt4, in red starfish, with their expression patterns suggesting a role in wound healing and regeneration.

This study found that the presence of benzeneseleninic acid in commercial anhydride samples lowered the reaction rate during the oxidation of a finasteride intermediate compared to pure anhydride.

This study found that γδ T cells play a role in regulating stromal behavior, influencing the composition and vascularity of fibrotic tissues during the foreign body response.

This study reviews methods to ensure the reliability of machine learning models in medical imaging, focusing on bias detection, data drift assessment, and accuracy estimation without ground truth labels to enhance integration into clinical settings.

This study developed a culture method to expand and differentiate primary mammary basal cells, identifying key transcription factors like EGR1 and ELF3 that influence Claudin expression and actin organization, offering insights into epithelial cell biology and potential applications in related research fields.

This study found petroleum ether to be more effective than methanol at extracting β-sitosterol from Eclipta alba, with higher concentrations detected using HPTLC and HPLC methods. The extracted materials contained metals within safety limits.

This study found that exosomes derived from hypoxia-conditioned mesenchymal stem cells modulated inflammatory biomarkers by decreasing CXCL12 and increasing IL-10 expression in a DHT-induced androgenic alopecia mouse model, indicating potential for treating hair loss through immunoregulation.

This review highlights that obsessive-compulsive disorder and body-focused repetitive behaviors are increasingly encountered in dermatology, often going undetected, and emphasizes the role of dermatologists in early identification and interdisciplinary treatment to address both physical and psychological aspects for improved outcomes.

This study investigated the effects of ultrasound-assisted extraction on sunflower seed oil mixed with defective green coffee grains, finding that higher coffee grain ratios decreased oil yield but increased phenolic content and antioxidant activity, with potential applications for wound treatment.

In this study, researchers identified an elite germplasm of the medicinal plant Eclipta alba, known for its liver disease benefits, with higher growth, yield, and wedelolactone content, suitable for large-scale cultivation to reduce strain on wild populations.

This case report described a 43-year-old male with trichotillomania, experiencing severe alopecia and an ulcerated plaque, who improved with a combination of antibiotic, antidepressant, and psychotherapy treatments, suggesting that these interventions may benefit individuals with psychiatric comorbidities linked to this condition.

This study found that extracts from Cirsium japonicum var. spinossimum seeds are rich in polyphenols and flavonoids, demonstrating significant anti-inflammatory and cell proliferation effects in specific cell models, suggesting potential as a source for anti-inflammatory and anticancer agents.

Pharmacists play a crucial role in patient care and education.