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      Clinical Manifestations of Cutaneous Lupus Erythematosus

      research Clinical manifestations of cutaneous lupus erythematosus

      148 citations , February 2005 in “Autoimmunity Reviews”
      This article discusses the distinct skin findings associated with lupus erythematosus, noting that some are specific to lupus while others are nonspecific and occur with various diseases; it reports no new results.
      Ichthyosis

      research Ichthyosis

      147 citations , January 2003 in “American journal of clinical dermatology”
      This review discusses various forms of ichthyosis, including genetic and acquired types, detailing their characteristics, causes, and potential management strategies, but reports no new clinical results.
      WNT Signaling in Disease

      research WNT Signaling in Disease

      144 citations , August 2019 in “Cells”
      This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.
      Lupus Erythematosus: Systemic and Cutaneous Manifestations

      research Lupus erythematosus: systemic and cutaneous manifestations

      144 citations , September 2006 in “Clinics in Dermatology”
      This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
      Tactile Innervation Densities Across the Whole Body

      research Tactile innervation densities across the whole body

      142 citations , September 2020 in “Journal of neurophysiology”
      This study estimates that young adults have about 230,000 tactile afferent fibers innervating their skin, with density varying by region and decreasing with age.
      Dermatological Adverse Events with Taxane Chemotherapy

      research Dermatological adverse events with taxane chemotherapy

      141 citations , September 2016 in “European Journal of Dermatology”
      This review examines dermatological side effects of taxane chemotherapy reported in past studies and highlights the necessity for identifying and managing these conditions to maintain cancer patients' quality of life; it presents no new clinical results.
      A Perspective on RNAi-Based Biopesticides

      research A Perspective on RNAi-Based Biopesticides

      140 citations , February 2020 in “Frontiers in Plant Science”
      This article discusses the potential of RNA-based biopesticides for sustainable agriculture and reports no new experimental results; it highlights the need for improved delivery systems and regulatory development to enhance deployment.
      Microneedles as the Technique of Drug Delivery Enhancement in Diverse Organs and Tissues

      research Microneedles as the technique of drug delivery enhancement in diverse organs and tissues

      140 citations , December 2017 in “Journal of Controlled Release”
      This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.
      Transplantation Immunology: Solid Organ and Bone Marrow

      research Transplantation immunology: Solid organ and bone marrow

      139 citations , February 2010 in “ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology”
      This review outlines the advancements in organ and tissue transplantation since the discovery of the human MHC and reports no new clinical results.
      Androgenetic Alopecia in Women

      research Androgenetic Alopecia in Women

      139 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”
      This article reviews androgenetic alopecia in women, highlighting diagnosis criteria and noting that topical minoxidil is currently the only proven treatment for hair growth; it reports no clinical trial findings.
      Morpho-Regulation of Ectodermal Organs

      research Morpho-Regulation of Ectodermal Organs

      131 citations , March 2004 in “˜The œAmerican journal of pathology”
      This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.
      Tregs: Where We Are and What Comes Next?

      research Tregs: Where We Are and What Comes Next?

      130 citations , November 2017 in “Frontiers in Immunology”
      This review explores recent findings on regulatory T cells, focusing on their unique functions in non-lymphoid tissues and new mechanisms of action, but presents no original clinical results.
      Hair Loss in Women

      research Hair Loss in Women

      129 citations , October 2007 in “The New England Journal of Medicine”
      This article discusses the evaluation and management of a 45-year-old woman with diffuse scalp-hair loss and reports no new clinical findings.
      Hormesis And Medicine: Biphasic Dose-Response Relationship

      research Hormesis and medicine

      127 citations , June 2008 in “British Journal of Clinical Pharmacology”
      This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.
      Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents

      research Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents

      127 citations , December 2007 in “Journal of Investigative Dermatology”
      This review examines regenerative hair waves and complex hair cycle domains in transgenic mice, highlighting how these dynamic processes contribute to skin regeneration and the physiological regulation of organs, but reports no new experimental results.
      Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      research Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      124 citations , October 2019 in “Frontiers in Immunology”
      This review discusses the role of the JAK-STAT pathway in autoimmune skin diseases and suggests potential therapeutic benefits of JAK inhibitors, but reports no new experimental results.
      From Causes of Aging to Death from COVID-19

      research From causes of aging to death from COVID-19

      122 citations , June 2020 in “Aging”
      This review discusses the hyperfunction theory of aging as a key factor in COVID-19 vulnerability, highlighting the potential of anti-aging interventions like rapamycin to reduce this risk.
      Histopathology of Non-Scarring Alopecia

      research Histopathology of non-scarring alopecia

      122 citations , April 1995 in “Journal of Cutaneous Pathology”
      The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
      Permanent Alopecia After Cranial Irradiation: Dose–Response Relationship

      research Permanent alopecia after cranial irradiation: Dose–response relationship

      120 citations , October 2004 in “International journal of radiation oncology, biology, physics”
      In this study, the researchers established a dose–response relationship between the hair follicle dose during cranial irradiation and the development of permanent alopecia, with other factors showing limited correlation.
      Zinc: An Essential Trace Element for Parenteral Nutrition

      research Zinc: An Essential Trace Element for Parenteral Nutrition

      114 citations , October 2009 in “Gastroenterology”
      This review discusses zinc's role as an essential trace element in human nutrition, particularly its importance in total parenteral nutrition, and reports no new clinical results.