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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.

Targeting TGFβ can improve skin immunity in older people.

Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.

DNMT3A is crucial for healthy skin and hair growth.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.

Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.

Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.

Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.

Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

Blocking Prostaglandin D₂ may help treat hair loss.

Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.