9 citations
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December 2022 in “Antibiotics” This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.
3 citations
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December 2023 in “International Journal of Nanomedicine” Repaglinide-loaded liponiosomal hybrids improve blood sugar control and insulin release better than regular Repaglinide.
February 2023 in “International Journal of Pharmaceutics” In this study, the researchers developed minoxidil cubosomes using nanotechnology, which improved drug penetration in the skin, showed greater hair growth efficacy, and reduced adverse skin reactions compared to traditional minoxidil solutions.
December 2025 in “Journal of Drug Discovery and Therapeutics” This review discusses spanlastics, advanced elastic vesicles used in drug delivery to enhance bioavailability of poorly soluble drugs, offering improved stability and targeted delivery compared to traditional systems like liposomes and nanoparticles, thus reducing side effects and enhancing therapeutic outcomes.
April 2025 in “Journal of Advances in Medical and Pharmaceutical Sciences” This review highlights the potential of spanlastics, a new type of drug delivery system, to enhance drug administration by offering better deformability and stability compared to other nanocarriers, potentially improving targeted drug delivery across various applications.
January 2023 in “The Egyptian Journal of Hospital Medicine” This study found that topical valproic acid and 5% minoxidil both significantly increased hair count in patients with female pattern hair loss, suggesting topical valproic acid as a potential treatment option.
January 2023 in “Records of Pharmaceutical and Biomedical Sciences” This review discusses the advantages and properties of mucoadhesive buccal dosage forms and reports no new clinical findings; the authors emphasize the potential of spanlastics as flexible, biodegradable drug carriers.
2 citations
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November 2024 in “AAPS PharmSciTech” In this study, researchers found that niosomes, bilosomes, and spanlastic formulations can enhance the oral anticoagulation efficiency of rivaroxaban in rats, with spanlastic ranked as the most effective in prolonging clotting, prothrombin, and tail bleeding times compared to unprocessed rivaroxaban.
January 2022 in “Elsevier eBooks” This study found that sodium valproate nanospanlastics could be an effective and safer method for treating androgenic alopecia, with results comparable to minoxidil but fewer side effects.
October 2018 in “Annals of Reviews & Research” This open-access journal publishes innovative research articles across various fields but reports no new clinical results in this summary.
January 2026 in “RSC Advances” This study found that the natural polymer-based hydrogel Gel/SA@PL released growth factors in a controlled way, which enhanced tissue regeneration and minimized scarring in the healing of diabetic wounds.
This study examined the use of keratin gel as a filler in nerve guides for peripheral nerve regeneration in a rat sciatic nerve injury model.
March 2023 in “International journal of pharmaceutical sciences review and research” In this study, an Emulgel containing Tridax procumbens extract was formulated and found to have promising physical properties and antimicrobial activity for wound healing.
July 2016 in “Dermatologie pro praxi” This article discusses the use of Espumil foam base in pharmacies for preparing dermatological medications and reports no new clinical results.
This study concluded that using Plasma gel and PRP as autologous collagen biostimulators improved acne scars and skin density, demonstrating efficiency and safety for facial rejuvenation in clinical evaluations including patient satisfaction.
9 citations
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June 2021 in “International Journal of Pharmaceutics” This study found that polymeric micelle nanocarriers delivered pharmacologically relevant amounts of spironolactone to the epidermis and upper dermis, with higher delivery to pilosebaceous units, suggesting potential for treating glucocorticoid-induced impaired wound healing and pilosebaceous androgen-related skin diseases.
8 citations
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September 2023 in “Advanced Pharmaceutical Bulletin” In a double-blind clinical trial, this study found that a gel containing chitosan-coated spironolactone nanoparticles effectively reduced acne lesions over 8 weeks without adverse skin effects, suggesting potential for enhanced acne treatment through targeted skin delivery.
The study reported that a poly herbal gel containing Lagenaria siceraria, Trichosanthis cucumarina, and Tridax procumbens promoted hair growth in human volunteers, with noticeable effects observed after 90 days.
January 2025 in “International Journal of Pharmaceutical Research and Applications” In this research, topical gels using natural mucilages from okra and hibiscus were successfully formulated to deliver diclofenac diethylamine, with hibiscus mucilage at 10% showing the best performance as a gelling agent based on various physicochemical tests.
6 citations
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August 2020 in “International Research Journal on Advanced Science Hub” In this study, researchers developed a niosomal gel system for transdermal delivery of testosterone, reporting strong penetrative capability, good spreadability, and a promising in vitro drug release profile, suggesting it may be an effective alternative for reducing the side effects of steroid treatments.
2 citations
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September 2023 in “JAAD Case Reports” This article discusses the chronic inflammatory skin diseases acne keloidalis nuchae and dissecting cellulitis of the scalp, focusing on their shared etiology and differing progression, and reports no new clinical findings.
31 citations
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September 2019 in “Acta Pharmacologica Sinica”
November 2021 in “International journal of life science and pharma research” This study reported that a solid lipid nanoparticle-based gel formulation, specifically optimized for psoriasis, improved drug loading capacity and release properties using high-pressure homogenization, suggesting its potential efficacy as a topical treatment.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.
1 citations
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July 2022 in “Journal of Drug Delivery Science and Technology” This study found that Spironolactone-loaded ethosomal gels provided superior skin permeation and deposition compared to niosomal gels in rabbit skin, suggesting that ethosomal gels could be a promising formulation for further clinical studies on treating androgenic alopecia.
1 citations
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April 2009 in “Expert Review of Dermatology” This study found that the once-daily gel combining calcipotriene and betamethasone dipropionate was more effective and faster in treating scalp psoriasis compared to individual treatments, with a similar safety profile.
24 citations
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September 2020 in “Pharmaceutics” In this study, solid lipid microparticles loaded with lidocaine hydrochloride were developed to effectively deliver pain relief and antimicrobial benefits for wound management, demonstrated by testing with bioengineered skin substitutes and showing effectiveness against common wound-infecting bacteria.
June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
This study found that an extract treatment showed similar efficacy and tolerability to calcipotriol/betamethasone ointment in reducing psoriasis severity and symptoms over 28 days in patients with mild-to-moderate plaque psoriasis.
April 2023 in “International journal of pharmaceutical sciences review and research” This study concluded that an Emulgel formulation containing Tridax procumbens extract showed promising wound healing and antimicrobial activity, with improved physical properties in the F2 formulation.