48 citations
,
February 2016 in “Scientific Reports” This study reports the creation of rat liver stem cell lines that can differentiate into hepatocytes and suggests they might be useful for pharmacological and regenerative medicine applications.
30 citations
,
April 2007 in “Dermatologic Clinics” This review discusses the mechanisms by which isotretinoin and hormonal therapy treat acne through their effects on sebaceous glands, reporting no new clinical results.
28 citations
,
March 2016 in “Toxicologic pathology” This review discusses the function and pathology of hair follicles and highlights the potential of using dogs as a model to study human hair and stem cell disorders, but presents no new experimental results.
23 citations
,
December 2006 in “Evaluation and Program Planning” This article presents a model for evaluating public R&D that emphasizes measuring capacity-based metrics over traditional outcome-based metrics, using the concept of a Knowledge Value Collective.
17 citations
,
November 2000 in “Journal of the American Pharmaceutical Association” This review discusses the perimenopause, its symptoms, and management options, emphasizing the role of pharmacists in educating and advising women on treatment strategies and preventive health measures, but it reports no new results.
14 citations
,
January 2018 in “Advances in Clinical Chemistry” This review discusses the evaluation of hyperandrogenemia in women and hypogonadism in men across different life stages and presents biomarkers used for diagnosing male hypogonadism, reporting no new clinical results.
11 citations
,
February 2021 in “Trends in Food Science and Technology” This review explores the potential of edible flowers, particularly the genus Impatiens, for their chemical, nutritional, and bioactive properties but does not report new clinical findings.
10 citations
,
December 2024 in “EXPERIMENTAL ANIMALS” This study found that aged C57BL/6 mice sub-strains exhibit distinct aging patterns, including differences in survival rates, body weight changes, and disease incidences, providing valuable insights for geriatric research using these mice models.
9 citations
,
May 2021 in “Immunological Reviews” This review discusses the role of fibroblast heterogeneity in kidney pathology, particularly their contribution to tertiary lymphoid tissue formation, and reports no new results.
9 citations
,
July 2018 in “Acta biomaterialia” This study reports a good correlation between the curvature of human eyelashes and the displacement of the neutral axis, influenced by the non-uniform thickness of the outer cuticle layer.
9 citations
,
January 2011 in “EXPERIMENTAL ANIMALS” This study describes a novel hairless mutant rat strain, F344-Hr(krh), developed via ENU mutagenesis, which provides a model for skin disease and potentially focal glomerulosclerosis due to specific genetic mutations.
8 citations
,
March 2020 in “Frontiers in Cell and Developmental Biology” This study developed a DPC cell line by introducing mutant CDK4, Cyclin D1, and TERT, making it a promising tool to study downstream signaling pathways activated by testosterone in androgenetic alopecia.
5 citations
,
January 2006 in “Journal of veterinary medical science” This study found that small amounts of RNA present in horsehair roots can be used for molecular biological analysis, although detecting mRNA transcripts in the hair shaft is more challenging.
3 citations
,
February 2021 in “Molecules” In this study, researchers developed a sensitive assay to measure the inhibition of steroid 5-α reductase (5AR) by chemicals like finasteride and dutasteride, revealing species-specific differences in inhibitor efficacy between human and fish cell lines.
1 citations
,
January 2017 in “Spectrum Research Repository (Concordia University)” This study found that young women with PCOS exhibited altered white matter microstructure and reduced cognitive performance compared to matched controls.
1 citations
,
March 2020 in “Functional foods in health and disease/Journal of functional foods in health & disease” This study found that OM-X® supplementation effectively prevented adverse biological changes caused by vitamin C deficiency in SMP30/GNL KO mice, improving energy maintenance, antioxidant capacity, and protein synthesis.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that the efflux of calcium in root hairs of Arabidopsis thaliana, particularly through the ER-localized ACA2 and ACA7, is crucial for modulating cytoplasmic calcium signals and enabling proper root hair growth, with disruptions leading to impaired elongation.
March 2026 in “Aesthetic Plastic Surgery” This review discusses the integration of Artificial Intelligence in non-surgical cosmetic procedures, highlighting its potential to improve personalized aesthetic care and operational efficiency while addressing ethical and regulatory challenges; it presents no new clinical findings.
August 2020 in “Textile research journal” This study introduces a modular fiber model to investigate how changes in microstructural properties of wool affect its critical buckling load, highlighting potential uses and areas needing further research in wool fiber biophysics.
December 2013 in “Research Portal (King's College London)” This article discusses the anatomical and biological aspects of hair follicle stem cells in the bulge region but reports no new research findings.
16 citations
,
August 2007 in “Histopathology” This case report describes a functional adrenocortical oncocytoma that co-secreted testosterone and cortisol.
12 citations
,
January 2005 in “Journal of Cosmetic Dermatology” This review discusses the natural progression of androgenetic alopecia and potential factors influencing its long-term prognosis, reporting no new clinical results.
This review critically analyzes recent literature on the use of nanotechnology in alopecia treatment, reporting promising results for improving drug delivery and hair growth, though challenges in maintaining physical stability may limit large-scale commercialization.
268 citations
,
April 2009 in “International Journal of Pharmaceutics” In this study, niosomal formulations enhanced minoxidil skin accumulation compared to commercial and control solutions, suggesting a potential improvement for topical delivery in hair loss treatment.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.
451 citations
,
March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
295 citations
,
September 2006 in “Cell Cycle” This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.
242 citations
,
February 2016 in “Science” This research found that Foxc1 transcription factor and COL17A1 are critical in regulating quiescence and hair thinning in hair follicle stem cells, with aging-related DNA damage leading to hair loss.
215 citations
,
January 2011 in “Reproductive Biology and Endocrinology” Among reproductive-aged women in Iran, this study found that the prevalence of PCOS varied significantly depending on the diagnostic criteria used, with estimates ranging from 7.1% to 14.6%.
185 citations
,
June 2011 in “Molecular and cellular endocrinology” This review discusses the regulation and function of vitamin D and its receptor in skin cells, highlighting their roles in processes such as proliferation inhibition, differentiation, and innate immunity, but reports no new results.