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This study observed that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments; linear filaments stabilize fused membranes, while branched filaments, connected by the protein Ezrin, drive integration, demonstrating actin's role in adapting to membrane biophysical changes.

In this study, researchers used spatial transcriptome profiling to identify immune disturbances in the peri-infundibular region of androgenetic alopecia patients’ hair follicles, finding increased CD4+ T cells with a bias toward Th2 immune responses compared to controls.

In this study, researchers observed a high degree of plasticity in somatosensory axons innervating Merkel cells in adult mouse skin, with both epithelial and neural components exhibiting dynamic remodeling, highlighting intricate epithelial-neural interactions in maintaining homeostasis.

This study in adult mice found that somatosensory axons innervating Merkel cells in the skin are highly plastic, with significant remodeling in response to epithelial turnover, and that Merkel cells play a role in limiting axonal branching and promoting their maturation.

This study suggests that caveolin-1 may be a potential target for treating psoriasis, as its downregulation was linked to psoriasis markers that improved with soluble caveolin scaffolding domain peptide treatment.

In this study, researchers developed a detailed spatial atlas of healthy human skin and basal cell carcinoma, revealing that basal cell carcinoma likely originates from hair follicles and involves expansion of specific fibroblast subpopulations found in healthy skin.

This study found that in adult mouse skin, somatosensory axon plasticity is highly dynamic and influenced by epithelial-neural crosstalk and intrinsic neural mechanisms.

This study found that a mathematical model predicts signaling heterogeneity in epithelial outer root sheath cells is necessary for hair follicles to maintain size and grow long hair fibers, supported by molecular experiments.

This research on dermal papilla cells found that Sparasis crispa increased mRNA expression related to hair production and may help in hair generation cycles, but its impact on male hair loss treatment remains uncertain.

This study suggests that the "spade sign" is a highly specific histopathologic feature of acne keloidalis, although its absence does not rule out the condition.

This case study describes a young girl with sparse, brittle scalp hair and multiple keratotic papules, but no systemic or familial abnormalities were found.

This study presents a machine learning algorithm that achieved 89.5% accuracy in predicting hair health using factors like spatial-temporal images, age, and gender.

African spiny mice can regenerate skin and hair after wounds due to specific tissue mechanics.

This study found that while epidermal PLCγ1 is not necessary for keratinocyte differentiation in interfollicular epidermis, it is crucial for normal hair and sebaceous gland formation in mice.

Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.

This study identified TGFβ-2 as a potential driver of progenitor cell loss in hair follicles from early androgenetic alopecia scalps, suggesting its role in the condition's molecular disturbances.

This article reviews the challenges of fasting and dietary regimens in producing sustained weight loss and reports no new research findings or results.

This study reported the discovery of large-scale haplotypes (cenhaps) in human centromere regions, revealing deep genetic diversity, including introgressed Neanderthal and ancient African lineages.

This study found that hippocampus sparing whole brain radiation therapy (HS-WBRT) using multi-field intensity modulated radiation therapy prevents alopecia without compromising cognitive function compared to traditional whole brain radiation therapy.

This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.

This study found that most chronic alopecia areata patients treated with azathioprine, methotrexate, or cyclosporine continued treatment for at least 12 months, often requiring concurrent low-dose prednisolone.

This case report describes how a treatment with mycophenolate mofetil and prednisone may be effective in managing autoimmune subepidermal blistering dermatosis in dogs while allowing for steroid reduction.

This study demonstrated a validated UPLC method for analyzing finasteride in low-dose drug products, highlighting methanol content and flow rate as critical factors for method robustness and accuracy.

This study in western Hudson Bay, Canada, examined trace elements in the hair of adult male polar bears and found significant differences in concentration patterns along the hair length, suggesting laser ablation ICP-MS is a promising tool for monitoring these variations over time.

This study found that human centromeric regions exhibit large-scale haplotypes with significant diversity, including entire Neanderthal haplotypes, which may affect chromosome transmission.

This study found that introducing the recombinant rat OTC gene into SPF-ASH mice restored normal hair growth and metabolic function, improving symptoms associated with OTC deficiency.

This study analyzed the geometric and electronic properties of baicalin conformers, finding that BCLa2TT and BCLa1TT conformers exhibit high stability in aqueous solutions and are favorable for interactions with positively charged species.

This paper reviews total skin electron therapy for mycosis fungoides and reports no new results; the authors focus on dose de-escalation's impact on toxicity and response rates.

This study developed a multiscale spatial atlas of healthy skin and basal cell carcinoma, revealing a hair follicle origin for BCC and the expansion of specific cell populations such as POSTN+ fibroblasts and RGS5+ pericytes, suggesting roles in skin cancer stroma expansion and vascular remodeling.