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SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Parsley contains compounds that might be good for treating hair loss.

Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.

Cannabinoids may help treat various skin conditions.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Medications for PCOS don't seem to raise heart disease risk.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.