April 2026 in “Journal of Dermatological Science” This study highlights that hair-bearing organoids derived from embryonic stem cells can effectively model androgenic alopecia conditions and test the efficacy of anti-hair loss treatments.
47 citations
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April 2003 in “Journal of dermatological science” This study showed that Thujae occidentalis semen extract inhibited 5alpha-reductase type 2 in laboratory tests and reduced androgen-related hair loss in animal models, suggesting potential use for male pattern baldness.
34 citations
,
August 2005 in “Dermatologic Clinics” This review discusses how the brain can influence skin biology, suggesting a link between psychological factors and skin health, but it reports no new scientific findings.
December 2019 in “University of Malaya Students Repository” This study found that Soxhlet extraction is more effective at removing the toxin mimosine from Leucaena leucocephala, and mimosine shows promise as a biodiesel additive due to its antioxidative properties.
2 citations
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June 2023 in “Journal of clinical medicine” This review found that both oral and topical soy-based products showed positive effects on various skin-related outcomes, including aging signs and skin barrier function, but topical applications were more likely to improve skin barrier status compared to oral supplementation.
1 citations
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May 2022 in “International Journal of Health Sciences (IJHS) (En línea)” This research reports the presence of various physicochemical constituents and nutrients in glycine max (soybean) milk and okara, highlighting its potential medicinal and nutritional benefits.
6 citations
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October 2011 in “InTech eBooks” This article reviews carbohydrate metabolism in plants, focusing on enhancing soybean product diversity and quality, and reports no new research results.
This study concluded that topical soy may improve skin tone, texture, and reduce hyperpigmentation while also inhibiting UVB-induced erythema and affecting hair texture.
1 citations
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July 2017 in “Microbial Cell Factories” This study found that supplementing soybean oil significantly increased the production of the cyclosporine A derivative [(4'-OH)MeLeu]4-CsA by 55.6%, offering potential enhancements for its clinical application.
January 2025 in “Journal of Medicinal Food” This abstract mentions that while synthetic drugs like minoxidil and finasteride for androgenic alopecia have side effects, the characteristics of popular natural alternatives, such as soybean, remain largely unreported, despite consumer preference for these products.
April 2017 in “The FASEB Journal” In this study, a soy-containing diet significantly reduced the incidence of colonic polyps in mice compared to a soy-free diet, suggesting that soy foods might lower the risk of colon cancer development.
This study observed that consuming soybeans for three months was associated with improved hair health in individuals with varying types of hair loss.
3 citations
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January 2009 in “Elsevier eBooks” This review discusses soy's potential benefits for skin, hair, and nails, noting that while skin and nail improvements are more pronounced, hair benefits are modest; it reports no new clinical results.
25 citations
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September 2013 in “Journal of thoracic oncology” In this animal study, soy isoflavones were found to protect lung tissue from the adverse effects of radiation, such as skin injury, inflammation, and fibrosis, suggesting a potential radioprotective benefit.
March 2024 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that substituting soy hulls for corn-based supplements did not significantly affect ewe growth, reproductive performance, or lamb performance in pasture-based hair sheep systems.
2 citations
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October 2008 in “InTech eBooks” This review discusses the benefits of non-denatured soybean extracts in skincare, suggesting potential roles in skin lightening, anti-aging, delaying hair growth, and photoprotection, but it reports no new clinical results.
43 citations
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December 2017 in “BMC Plant Biology” This study found that strigolactone biosynthesis and signaling components in soybean may interact with other hormone pathways, influencing soybean development and nodulation.
26 citations
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May 2021 in “International Journal of Molecular Sciences” In this review, researchers examined the physiological benefits of Cheonggukjang, a salt-free fermented soybean paste, highlighting its various health-promoting components that may contribute to improved heart health, diabetes management, and cancer prevention, among other benefits.
13 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that the fermented black soybean product GR-SC65 reduced particulate matter-induced cell death and oxidative stress in A549 cells, suggesting potential as a therapeutic agent for lung injury prevention.
January 2026 in “http://isrctn.com/” The supplement may improve hair growth and quality in women with mild to moderate hair loss.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
October 2012 in “International journal of radiation oncology, biology, physics” This study found that soy isoflavones protected normal lung structures in mice against radiation-induced inflammation, damage, and increased breathing rate following radiation treatment.
March 2019 in “Digital Access to Scholarship at Harvard (DASH) (Harvard University)” This study found that soy-based nanofibrous scaffolds enhanced wound closure and tissue regeneration via the ER-β pathways in both mouse and human skin, suggesting a potential for effective wound healing applications.
1 citations
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January 2003 in “Expert Opinion on Therapeutic Patents” This review discusses the development and potential therapeutic applications of steroid sulfatase inhibitors for hormone-dependent disorders and cognitive dysfunction, reporting no new clinical results.
451 citations
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March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
April 2020 in “Journal of the Endocrine Society” In this case study, the use of somatostatin analogues was effective in localizing and confirming a neuroendocrine lung tumor as the source of ectopic ACTH syndrome, leading to marked clinical improvement in a patient unable to undergo surgery.
22 citations
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July 2011 in “EFSA journal” There is not enough evidence to support health claims about soy isoflavones.
January 2025 in “Journal of the Korean Society of Food Science and Nutrition” This study found that the combination of finasteride and black soybean extract showed synergistic protective effects against DHT-induced damage in hair follicle cells, suggesting potential benefits for treating androgenetic alopecia.
5 citations
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September 2023 in “Nutrients” In this study, a 6-month randomized controlled trial with postmenopausal women reported that supplementing with soy protein isolate with isoflavones led to significant improvements in skin hydration and reduced wrinkles and facial pigment intensity, but did not affect sebum production.
17 citations
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March 2004 in “Journal of Investigative Dermatology” Soymetide-4 from soy can prevent hair loss caused by a cancer drug in rats.