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Skin-derived stem cells could help treat skin aging and pigmentation issues.

In this study, researchers observed that dormant TRP-2+ melanoma cells in bone marrow can interact with CD8+ T cells in tumor-bearing ret transgenic mice, potentially influencing immune responses.

This study found that knock-down of keratin 15 in various cell lines affected cell spreading, morphology, migration, differentiation, and proliferation, suggesting its role in maintaining the stem cell nature of keratinocytes.

This study found that knocking out the integrin β1 subunit in induced pluripotent stem cells enhanced their migration and improved their wound-healing effects in a mouse model.

This study demonstrated that combining the Wnt/β-catenin activator CHIR99021 with 3D spheroid culture effectively enriched hair follicle formation in reconstituted human skin.

This study identified a distinct CD49fhigh mesenchymal stem cell subpopulation in the dermis that supports hair follicle development and maintenance via Notch signaling activation.

This study suggests that mouse lineage specification during pre-implantation development involves distinct timing and mechanisms for trophectoderm and inner cell mass differentiation, challenging existing models.

In this study, human dermal stem/progenitor cell-derived conditioned medium was found to promote hair regrowth in mice, possibly through effects on the Wnt/β-catenin pathway.

In this study, neonatal mouse mesenchymal cells showed hair-inducing capabilities, which were lost during in vitro propagation but could be partially restored through specific high-density culture methods.

OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.

This study found that human hair follicle-derived mesenchymal stem cells effectively maintained human embryonic stem cells in an undifferentiated state, comparable to mouse embryonic fibroblasts under standard conditions.

In mouse models, this study showed that transplanted dermal papilla and dermal sheath cells can integrate into hair follicles, promoting hair growth and extended anagen phases, with their effectiveness influenced by factors such as immune response and cell passage number.

This study observed that GREM2 was specifically and robustly expressed in the dermal sheath cup of hair follicles during various hair cycle phases, suggesting its significant role in regulating hair cycling processes through BMP signaling.

This study found that adipose-derived stem cells with DKK1 knocked out using CRISPR/Cas9 promoted hair growth in an alopecia areata model more effectively than untreated stem cells, suggesting DKK1 is a potential therapeutic target for this condition.

This study found that Blimp1 plays a key role in promoting hair follicle morphogenesis and growth by mediating inductive signaling pathways in dermal papilla cells.

This study confirmed the biological characteristics and multipotent differentiation potential of primary and secondary hair follicle stem cells from Arbas Cashmere goats, contributing to the understanding of adult stem cell types and characteristics.

This review highlights the potential roles of long non-coding RNAs (lncRNAs) in malignant brain tumors, reporting that further research into their involvement in therapy resistance and cancer pathways could improve diagnosis and treatment outcomes.

This study observed that after hair cell loss in the mouse cochlea, supporting cells were replaced by migrating non-specialised cells, with genetic background affecting the rate of tissue re-organization.

This study found that during amelogenesis in Msx2 null mice, a dysfunctional enamel organ developed due to abnormal epithelial transformation and lacked proper enamel formation.

This study suggests that short-term treatments with specific small molecules may enhance the differentiation potential and stem cell properties of human amniotic fluid stem cells.

In this study, researchers identified two genetic mutations associated with producing finer and denser wool in fine-wool sheep, involving the genes KRT74 and EDAR, which may guide future breeding efforts to enhance wool quality.

Nephronectin helps attach muscle cells to hair follicles.

This review discusses the role of enhancers and super-enhancers in tissue-specific gene regulation and cancer development, and it reports no new experimental results.

This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.

This study identified key genes involved in hair follicle development in Merino sheep, offering insights for improving wool production and providing a basis for future breeding programs.

This study found that mesenchymal stem cells from adipose tissue and hair follicles have a similar ability to differentiate into neurons, which could aid in developing therapies for neurological diseases.

In this study, researchers found that while both hair follicles and skin dermis-derived neural crest stem cells are suitable for large-scale manufacturing, skin dermis cells grow faster and are easier to obtain.

In this study, researchers found that knocking down the transcription factor Csdc2 inhibited the proliferation of dermal papilla cells in cashmere goats, and identified its regulatory relationship with the gene Robo2, providing insights into the genetic mechanisms influencing cashmere fiber growth.

This study found that PSAT1 is a key regulator of cellular survival and regenerative capacity in cashmere goat hair follicle stem cells, highlighting its role in the SHF cycle and its potential as a target to boost cashmere fiber production.

This study categorizes the human fetal vaginal epithelium into four areas with distinct transcriptomic profiles, aiding potential advancements in vaginal reconstruction and drug delivery.