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      Cutaneous Complications of Chemotherapeutic Agents

      research Cutaneous complications of chemotherapeutic agents

      172 citations , November 1983 in “Journal of The American Academy of Dermatology”
      This article discusses the cutaneous side effects of various chemotherapeutic agents but reports no new clinical results; the authors emphasize the importance of dermatologists recognizing drug-induced skin reactions to better patient care.
      Epidermal Stem Cell Diversity and Quiescence

      research Epidermal stem cell diversity and quiescence

      168 citations , August 2009 in “EMBO molecular medicine”
      This review discusses epidermal stem cell diversity, revealing previously unrecognized differences in stem cell populations, but reports no new experimental results; it highlights the need for further exploration of stem cell interactions and quiescence.
      Early Inductive Events in Ectodermal Appendage Morphogenesis

      research Early inductive events in ectodermal appendage morphogenesis

      160 citations , January 2014 in “Seminars in cell & developmental biology”
      This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.
      The Harmonies Played by TGF-β in Stem Cell Biology

      research The Harmonies Played by TGF-β in Stem Cell Biology

      156 citations , December 2012 in “Cell Stem Cell”
      This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.
      The Pharmacology of Methotrexate

      research The pharmacology of methotrexate

      155 citations , August 1991 in “Journal of The American Academy of Dermatology”
      This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.
      Androgenetic Alopecia: A Review

      research Androgenetic alopecia: a review

      153 citations , March 2017 in “Endocrine”
      This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
      Alopecia Areata: A Multifactorial Autoimmune Condition

      research Alopecia areata: A multifactorial autoimmune condition

      148 citations , December 2018 in “Journal of autoimmunity”
      This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
      Clinical Manifestations of Cutaneous Lupus Erythematosus

      research Clinical manifestations of cutaneous lupus erythematosus

      148 citations , February 2005 in “Autoimmunity Reviews”
      This article discusses the distinct skin findings associated with lupus erythematosus, noting that some are specific to lupus while others are nonspecific and occur with various diseases; it reports no new results.
      WNT Signaling in Disease

      research WNT Signaling in Disease

      144 citations , August 2019 in “Cells”
      This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.
      K ATP Channels and Cardiovascular Disease

      research K ATP Channels and Cardiovascular Disease

      144 citations , March 2013 in “Circulation Research”
      This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
      Lupus Erythematosus: Systemic and Cutaneous Manifestations

      research Lupus erythematosus: systemic and cutaneous manifestations

      144 citations , September 2006 in “Clinics in Dermatology”
      This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
      Molecular Mechanisms of Viral Oncogenesis in Humans

      research Molecular mechanisms of viral oncogenesis in humans

      141 citations , August 2018 in “Nature Reviews Microbiology”
      This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.
      Protoporphyrin IX: The Good, the Bad, and the Ugly

      research Protoporphyrin IX: the Good, the Bad, and the Ugly

      138 citations , November 2015 in “Journal of Pharmacology and Experimental Therapeutics”
      This review discusses the mechanisms associated with protoporphyrin IX in living cells and reports no clinical results; the authors emphasize its potential in cancer diagnosis and the risks of toxicity.
      TGF-β Family Signaling in Stem Cells

      research TGF-β family signaling in stem cells

      132 citations , August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”
      This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.
      dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration

      research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration

      128 citations , August 2015 in “Cell Stem Cell”
      The researchers reported that dsRNA from damaged skin activates TLR3, promoting hair follicle regeneration, while TLR3-deficient animals fail to initiate this process, suggesting potential therapeutic approaches for hair neogenesis.
      Targeting the Wnt Pathways for Therapies

      research Targeting the Wnt pathways for therapies

      112 citations , January 2014 in “Molecular and cellular therapies”
      This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.