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The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

Shh and Dhh affect skin development and can cause tumors, while Ihh does not.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Sonic hedgehog helps hair follicle stem cells grow and can effectively regenerate hair follicles.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

Sonic hedgehog proteins may help grow hair.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.

Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

Muscles and nerves that cause goosebumps also help control hair growth.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.

Polygonum multiflorum can promote hair growth when taken orally or applied topically.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.