115 citations,
December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
72 citations,
April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
May 2023 in “BMC Women's Health” Many women who have used performance-enhancing drugs in Finland show high rates of mental health and substance use issues, and most have normal red blood cell counts.
56 citations,
October 2010 in “Pediatric Clinics of North America” Epidermal nevi are skin cell clusters linked to various syndromes.
15 citations,
September 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Skin doctors should recognize and treat conditions like hair-pulling and skin-picking early, often using therapy and medication, to help 50-70% of patients.
13 citations,
August 2005 in “Dermatologic Clinics” Doctors should consider psychological factors when treating skin conditions and work with mental health experts.
May 2023 in “Frontiers in Endocrinology” Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
January 2013 in “Kidney international” A man with kidney tumors and lung cysts was diagnosed with Birt–Hogg–Dubé syndrome and treated successfully, with genetic testing confirming the diagnosis.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
61 citations,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
10 citations,
January 2023 in “Journal of the European Academy of Dermatology and Venereology” Alopecia areata greatly affects people's life quality, mental health, and work life.
6 citations,
November 2022 in “Development” New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
128 citations,
October 2011 in “Development” Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
207 citations,
March 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
103 citations,
March 2015 in “Nature Communications” A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
111 citations,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
95 citations,
April 2013 in “PLOS ONE” Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.
80 citations,
March 2004 in “Neuropediatrics” Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.
39 citations,
March 2003 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” Behavioral dermatology treats skin problems by considering both emotional and physical factors.
31 citations,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
20 citations,
November 2012 in “Journal der Deutschen Dermatologischen Gesellschaft” Hair diseases can have psychological effects and should be treated with a combination of psychosomatic care, therapy, and medication.
9 citations,
February 2016 in “Cambridge University Press eBooks” The conclusion is that self-concept, shame, and emotion regulation are key factors in hoarding disorder, body dysmorphic disorder, and trichotillomania, and should be targeted in treatment and research.
4 citations,
January 2008 in “Food Science and Technology Research” Mature leaves of 'Saijo' persimmon have the most vitamin C and both mature leaves and new shoots are rich in polyphenols.
1 citations,
February 2024 in “International Journal of Pharmacognosy & Chinese Medicine” Hibiscus rosa-sinensis Linn. has many medicinal benefits and needs proper identification for effective use.
March 2024 in “International Research Journal Of Modernization In Engineering Technology And Science” Certain plants like Aloe vera and Neem are effective and safe for treating various skin conditions.
166 citations,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
160 citations,
January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
63 citations,
March 1998 in “Archives of Dermatology” Antidepressants may improve or resolve scalp dysesthesia in most patients.
55 citations,
January 2007 in “Climacteric” Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
48 citations,
January 2011 in “Hormone Research in Paediatrics” The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.