137 citations
,
April 2015 in “Nature Reviews Molecular Cell Biology” This review discusses the distinct roles and surprising developmental flexibility of multiple somatic stem cell types in tissue maintenance and repair, reporting no new results but highlighting emerging questions about their regulation and origins.
101 citations
,
August 2003 in “Journal of comparative neurology” In this study, naked mole-rats demonstrated unique skin and hair follicle innervation features compared to other species, suggesting adaptations to their subterranean environment and poikilothermy.
70 citations
,
February 2016 in “EMBO reports” This study identified a subtype of itch-sensing neurons in mice, which express Ret and somatostatin, and found that their ablation reduces scratching induced by certain pruritogens.
43 citations
,
September 2001 in “Annals of Neurology” This study found that somatic mosaic mutations in the doublecortin gene may cause subcortical band heterotopia in male patients, and molecular analysis using hair roots is a useful detection method.
43 citations
,
October 1955 in “The journal of nutrition/The Journal of nutrition” This study found that male germ-free rats fed semisynthetic diets do not grow as rapidly as their conventional counterparts and require dietary biotin for normal metabolism and folic acid biosynthesis.
34 citations
,
July 1958 in “Biochimica et Biophysica Acta”
27 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified somatostatin as a potential secretory factor contributing to the immune privilege of human hair follicles.
26 citations
,
June 2004 in “Clinical Genetics” This study describes a case of epidermolysis bullosa simplex where maternal somatic and germline mosaicism was identified, highlighting the significance for genetic counseling in sporadic cases.
25 citations
,
October 1962 in “Journal of Ultrastructure Research” The hair follicle structure is more complex than thought, with new findings on protein formation.
19 citations
,
March 1998 in “Endocrinology” This study found that sex differences in somatostatin biosynthesis in rat hypothalamic neurons develop between postnatal day 1 and 5, influenced by the conversion of testosterone to estrogen.
16 citations
,
March 2020 in “Animal Biotechnology” This research explored methods to obtain transgenic sheep embryos expressing synthetic spider silk genes in hair follicles using somatic cell nuclear transfer, with successful in-vitro development observed.
13 citations
,
January 2023 in “Annual Review of Cancer Biology” This study suggests that cancer risk may be influenced by the balance of pro- and anti-oncogenic mutants in normal tissues rather than by the total number of mutations.
11 citations
,
February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis” This study reports that treatment with X-rays or procarbazine induced dose-dependent mutations in melanocytes in mouse hair follicles, showing similar mutation rates to previous methods.
9 citations
,
January 2013 This study found that serum levels of zinc, copper, and selenium were significantly lower in patients with alopecia areata compared to healthy controls, regardless of the number of hair loss patches.
9 citations
,
January 1959 in “The journal of nutrition/The Journal of nutrition” This study found that a higher potassium diet in lysine-deficient rats partially protected against hair loss and increased liver fat, suggesting these rats require more potassium.
7 citations
,
July 2004 in “Endocrine practice” This case report highlights how persistent hyperphosphatemia, albeit often overlooked, can precede clinical acromegaly symptoms in women, complicating diagnosis due to overlapping features with oral contraceptive use and polycystic ovary syndrome.
6 citations
,
December 1966 in “Textile Research Journal” Animal hair fibers like wool and mohair are strong when dry, but vicuna fibers are very brittle.
5 citations
,
January 2017 in “Clinics in Dermatology” This review discusses the challenges of diagnosing and managing somatization in dermatology patients, highlighting the need for comprehensive evaluation of unexplained dermatologic symptoms, and reports no new results.
4 citations
,
June 2025 in “JMIR Formative Research” In this study, researchers reported no statistically significant association between hair cortisol levels and either perceived stress or objective neuroendocrine stress measures in a predominantly male participant group.
4 citations
,
August 2023 in “Italian Journal of Food Science” This study found that pretreatment combining maceration with press-shear force and moist heat significantly increased the total phenolic and flavonoid contents in galactagogue herbs like banana inflorescences and Thai ginger.
4 citations
,
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses the role of human scalp hair follicles in neurohormone production and their model potential for studying neuroendocrine signaling, reporting no experimental results.
4 citations
,
February 2013 in “PubMed” In this study, the antibody A3 identified quiescent post-progenitor epithelial and mesenchymal cells in developing rat hair follicles, suggesting it may help track the differentiation of these cells.
4 citations
,
December 1990 in “International Journal of Dermatology” This article discusses dermatoses unique to Sikh men and reports no new clinical findings.
3 citations
,
July 2018 in “DergiPark (Istanbul University)” This article reviews the usage of medicinal plants for treating certain conditions in European Turkey, detailing the plants' parts, preparatory methods, and traditional therapeutic applications but reports no new experimental results.
3 citations
,
December 2014 in “Annals of Laboratory Medicine” In this study, a somatic KRAS mutation was identified in a Korean infant with nevus sebaceus and associated extracutaneous manifestations, suggesting a diagnosis of nevus sebaceus syndrome.
2 citations
,
March 2003 in “DigitalResearch@Fordham (Fordham University)” This essay discusses the relationship between communication and a sense of self through the metaphor of material, drawing on a children's story to explore the material basis of storytelling and creation, without providing new research results.
1 citations
,
June 2025 in “Ukrains kyi Visnyk Psykhonevrolohii” This study found that psychopathological reactions, particularly cognitive impairments such as impaired concentration, are prevalent among patients with diffuse alopecia, with variations in prevalence linked to the genesis of alopecia, notably higher in mixed-type compared to metabolic-type alopecia.
1 citations
,
February 2023 in “Applied sciences” This study found that methylcellulose-based hydrogels can effectively deliver growth hormone through the skin, with albumin increasing the hormone's permeation to 93% in simulated in vivo conditions.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that human skin melanocytes with low mutation burdens are smaller, less dendritic, and exhibit stem-like features, often residing in UV-protected hair follicles, suggesting their role in replenishing sun-damaged epidermis.
November 2025 in “Вопросы современной педиатрии” In this case report, the researchers observed that combining growth hormone therapy with the biologic drug dupilumab effectively improved growth and health outcomes in a patient with Netherton syndrome and comorbid hypopituitarism, suggesting a multidisciplinary approach may be beneficial for managing such cases.