Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this review, the authors discuss caffeine's potential mechanisms and benefits as a hair loss treatment, noting its possible effectiveness and safety, though they caution that existing studies often have significant design flaws.

In this study, researchers evaluated male-pattern hair loss treatments using RNA and microRNA expression profiling in 91 male participants, identifying 52 differentially expressed genes and suggesting a potential role for personalized treatment based on genetic analysis to monitor and predict treatment efficacy and compliance.

This review highlights that human hair is a valuable biological matrix for clinical and toxicological analyses, demonstrating its applicability in detecting various active substances from different pharmacological classes.

This review explores the potential benefits of natural plant-based products for skin anti-aging, assessing effects on wrinkles, oxidative stress, pigmentation, and hydration, while also underscoring the importance of lifestyle factors such as diet, exercise, and sleep in skin health maintenance.

This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.

This review compiled evidence suggesting that flavonoids may promote skin wound healing due to their anti-inflammatory, angiogenesis, re-epithelialization, and antioxidant properties, while also discussing current limitations and future prospects for these compounds as wound-healing agents.

This study's simulation found that Ascorbyl Tetraisopalmitate penetrates more efficiently through the skin's stratum corneum than via the infundibulum, following different pathways and dynamics in each membrane.

This study found that the aerial parts (leaves and flowers) of Scorzonera undulata from southwest Tunisia demonstrated higher antioxidant activity and beneficial biological properties compared to its tubers.

This study found that extracts from Hom Thong banana peels, rich in phenolic compounds, may inhibit melanin production in human and mouse melanoma cells, showing potential as anti-melanogenic agents comparable to standard treatments like arbutin and kojic acid.

This study found that endophytic bacteria isolated from Leea indica leaves showed high antioxidant activity, suggesting they could be a novel source of natural antioxidants.

This review describes deep eutectic solvents as a green alternative to toxic solvents in extracting bioactive compounds, highlighting their sustainability, production from natural ingredients, and beneficial properties for pharmaceutical applications.

This study used machine learning to identify FDA-approved drugs afatinib, neratinib, and zanubrutinib as potential KRASG12C inhibitors for resistant non-small-cell lung cancer, highlighting the potential of AI in drug repurposing.

The study concluded that poly(propylene carbonate maleate) microspheres effectively encapsulated finasteride, achieving a biphasic release with prolonged drug release over 5-6 weeks in vitro.

In this study, researchers using a multi-omics approach identified specific proteins involved in the hair follicle cycle of Inner Mongolia Cashmere Goats, finding that API5 affects apoptosis, while ribosomal proteins are highly expressed during the resting stage, providing insights into hair follicle growth and apoptosis.

This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.

This study found that injecting nu/nu mice with aqueous dispersion of unmodified fullerene C60 significantly stimulated hair growth compared to controls, suggesting its potential as a new therapeutic approach for alopecia.

This study found that dietary vitamin E influenced gene expression in rat livers, altering genes related to metabolism, coagulation, and steroid processing, and confirmed its effects on related biological endpoints.

This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.

This study found that the ashwagandha extracts ASH-Ext1 and ASH-Ext2 show different pharmacological activities in cell models due to their distinct withanolide proportions, highlighting the need for standardized extraction protocols to ensure consistent therapeutic efficacy.

This study found that methanol is more effective than isopropanol at removing external cortisol from grizzly bear hair and suggests that the choice of solvent can influence hair cortisol concentration results.

This study found that shampoo and conditioner do not alter hair's molecular structure, while perming treatments significantly affect keratin and intermediate filament structures due to bond alterations.

This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.

In this study, perilla seed extract obtained through supercritical fluid extraction was found to promote hair follicle cell proliferation and downregulate key genes linked to androgenetic alopecia, showing potential as a natural treatment for hair loss in vitro.

In this study, molecular dynamics simulations indicated that the Glu413Lys mutation in human hair keratin significantly affects the stability of coiled coil structures, whereas Glu413Asp showed no impact on stability.

This review discusses the chemical composition, potential health benefits, and extraction methods of red ginseng oil, and reports no new clinical results but emphasizes safety and proposed molecular mechanisms.

This study predicted that key components of Platycladi Cacumen, such as quercetin and apigenin, may have stable binding interactions with targets involved in androgenetic alopecia.

This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.

This study found that a sub-fraction of Noni fruit, FEA-3, showed hair growth-promoting effects in a rabbit model of androgenic alopecia, similar to Minoxidil.

In this study, researchers used a network pharmacology approach to highlight significant interactions between compounds in rosemary (Salvia rosmarinus) and genes related to functional dyspepsia, suggesting potential pathways for developing treatments against gastrointestinal diseases.

This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.