January 2019 in “FarFar - Pharmacy Repository” This article reviews strategies like microemulsions to improve adapalene delivery in acne treatment but reports no new clinical results.
January 2022 in “Drug Delivery” This study investigated a finasteride and oregano oil-loaded nano-cubosome gel formulation, finding it enhanced drug release and skin permeation and demonstrated synergistic antibacterial effects, suggesting potential for treating alopecia areata.
43 citations
,
July 1994 in “Journal of Cell Science” This study found that the extraction-resistant structures in hair, feathers, and hagfish teeth are due to ε-(γ-glutamyl)lysine cross-linked proteins, emphasizing their role in maintaining the integrity of these materials.
21 citations
,
June 2002 in “International Journal of Cosmetic Science” Advancements in hair keratin research could lead to better hair health treatments.
17 citations
,
January 2016 in “Journal of Drug Delivery” In this study, PEG and keratin scaffolds selectively influenced protein release rates based on charge and size, suggesting their potential for targeted delivery of protein therapeutics.
9 citations
,
October 1957 in “A M A Archives of Dermatology” In this study, carotene injected into the skin was converted into vitamin A by sebaceous gland cells, where it was not normally detectable.
8 citations
,
January 2009 in “Transactions of the Materials Research Society of Japan” This study found that CMAD wool keratin may protect human hair from damage during repeated bleaching and permanent waving treatments.
7 citations
,
April 1996 in “British Journal of Dermatology” This study found that intermediate filaments and matrix proteins in presumptive hair shaft cells are synthesized sequentially, identifying a new polypeptide component that changes during hair cell differentiation.
This study introduced a technology for creating water-soluble minerals, which reportedly showed potential health benefits such as diet and anti-wrinkle effects in their applications.
559 citations
,
October 2020 in “Frontiers in Molecular Biosciences” This review reports on the current state and potential of solid lipid nanoparticles for drug delivery, emphasizing their safety, biocompatibility, and ease of production, and highlights challenges in translating them to clinical practice, including active clinical trials.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.
233 citations
,
February 2018 in “Polymers” This review examines the roles and benefits of chitosan in cosmetics and oral hygiene, highlighting its potential in the cosmeceutical market, but it reports no new results.
155 citations
,
August 1991 in “Journal of The American Academy of Dermatology” This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.
124 citations
,
January 2009 This article provides an overview of crystallization processes, challenges, and applications, discussing various techniques and examples, but it reports no new experimental findings.
75 citations
,
August 2006 in “International Journal of Pharmaceutics” The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
72 citations
,
June 2019 in “International Journal of Cosmetic Science” This review discusses the biological properties of 18β‐glycyrrhetinic acid derived from licorice root, highlighting its potential anti-inflammatory, antioxidant, and antimicrobial benefits in treating dermatological disorders, and reports no new experimental results.
61 citations
,
May 2014 in “International journal of pharmaceutics” This research describes a process for producing caffeine nanocrystals, which may enhance skin penetration by accumulating in hair follicles and maintaining stability for two months, paving the way for in vivo testing.
44 citations
,
April 2011 in “Critical reviews in analytical chemistry” This review discusses the pharmacological properties and analytical methods for determining fluconazole but reports no new experimental findings.
42 citations
,
July 2014 in “European journal of pharmaceutics and biopharmaceutics” This study established a stable formulation for caffeine nanocrystals in specific solvent mixtures, which could be used to test their potential for enhanced hair follicle targeting and penetration.
41 citations
,
June 2023 in “Antioxidants” This review highlights that pomegranate exhibits promising beneficial effects in preclinical and clinical studies for cardiovascular and non-cardiovascular diseases, though further research is needed on its bioavailability and metabolites for effective therapeutic use.
40 citations
,
October 2009 in “Journal of Biomedical Nanotechnology” This review discusses pyrene excimer nucleic acid probes for detecting biomolecules and protein-DNA interactions and reports no new experimental findings.
37 citations
,
November 2020 in “International Journal of Nanomedicine” Nano-liposol with astaxanthin may improve antioxidant and wound healing effects.
36 citations
,
September 2019 in “Journal of Herbal Medicine” This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.
36 citations
,
October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.
34 citations
,
July 2011 in “International journal of pharmaceutics” This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.
29 citations
,
September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
26 citations
,
June 2010 in “Electrophoresis” This study reported advances in identifying low-abundance proteins in wool by using fractionation techniques to reduce the dominance of intermediate filament proteins, improving the understanding of the wool proteome.
24 citations
,
January 2023 in “International Journal of Nanomedicine” This review outlines how combining biomembrane-based nanostructures and microstructures with hydrogels can enhance strategies for chronic wound healing, by utilizing the unique properties of both to address metabolic disturbances and severe symptoms in wound care.
22 citations
,
September 2024 in “Chemical Engineering Journal” A new microneedle patch effectively and safely treats alopecia areata.
18 citations
,
February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.