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Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.

Corin helps control salt and sweat release in sweat glands.

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.

Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.

Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Not getting enough minerals can lead to health problems and shorter lifespans.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

MR antagonists may improve skin health and wound healing, especially in aging.

Valproic acid microemulsions improve skin delivery compared to regular solutions.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

Using focused ultrasound on the brain can help epilepsy medicine work better in rats.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

A woman's eyelashes grew thicker and longer after taking topiramate, but returned to normal when she stopped the medication.

Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.

Extended-release valproate effectively reduced seizures and improved quality of life in epilepsy patients over 6 months, with some side effects.

Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.

Valproate can cause hair loss and changes in hair appearance, but may help regrow hair when applied topically.

Topical valproate can effectively promote hair growth.

Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.