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Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

Corin helps control salt and sweat release in sweat glands.

Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.

MR antagonists may improve skin health and wound healing, especially in aging.

Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Not getting enough minerals can lead to health problems and shorter lifespans.

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

Extended-release valproate effectively reduced seizures and improved quality of life in epilepsy patients over 6 months, with some side effects.

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

Topical valproate can effectively promote hair growth.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.