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This research reports that copper-quercetin complexes show strong potential in antioxidation and cancer therapy, while their effects on specific cell death pathways warrant further investigation.

This study found that estradiol significantly reduces cisplatin-induced cochlear hair cell death in mice, likely by activating Nrf2 and phase II detoxification enzymes.

This review discusses the evolution of adipose tissue research in regenerative medicine, from tissue transfer to cell-free bioengineering applications, highlighting its therapeutic potential, current limitations, and future directions.

This review highlights the multifunctional benefits of plant-derived ingredients in skincare, such as antioxidant and anti-inflammatory effects, supported by biological evidence from medicinal plants like Camellia sinensis and Panax ginseng, suggesting their potential as natural dermocosmetic agents.

This review highlights that hirsutism in the GCC is influenced by genetic and lifestyle factors, cultural stigmas, and lacks adequate diagnostic tools, stressing the need for culturally tailored research and public health initiatives.

This study found that components in the kernel of Prunus mira Koehne, such as vitamin E and β-sitosterol, may promote hair growth in mice, possibly involving the Wnt/β-catenin signaling pathway.

In this study, finasteride was shown to inhibit glioma stem-like cells and reduce glioblastoma proliferation, suggesting its potential as an anti-glioblastoma drug.

This study in mice found that maternal iron deficiency led to hair loss and growth abnormalities in offspring due to increased oxidative stress and disrupted signaling pathways, but postnatal iron supplementation was able to reverse these effects.

This narrative review highlights the need for diabetes-informed approaches to aesthetic dermatology as accelerated skin aging in diabetic patients complicates the safety and effectiveness of cosmetic procedures.

This review explores the potential roles of extracellular vesicles in various medical fields, emphasizing their promise but noting the need for standardization and clinical testing before widespread application.

This study found that 3-hydroxypropionic acid improved the function of hair follicle cells under oxidative stress, suggesting potential as a treatment for stress-related hair loss.

This review reports that biomaterial-based drug delivery systems show promise in overcoming the limitations of traditional therapies for pathological scars by integrating sustained drug release with minimally invasive transdermal technologies, potentially enhancing treatment efficacy for these challenging skin lesions.

This study highlights the critical role of mitochondria in skin aging and wound repair, suggesting that targeted interventions such as antioxidants, NAD⁺ boosters, and NRF2-based therapies may enhance mitochondrial function and improve cutaneous health.

This research concludes that adipose mesenchymal stem cells are uniquely evolved to manage skin inflammation in newborns and their released molecules are the safest and most effective for skin therapeutics.

In this study, cats fed trace minerals complexed with lysine and glutamic acid displayed temporary improvements in hair loss and dander scores at 45 days, compared to those receiving inorganic trace minerals, although no differences were seen by day 90.

This article provides a clinical update on alopecia areata, highlighting the disease's multifactorial causes, challenges it presents, and the current treatment options, with a focus on comparing international guidelines and discussing comorbidities.

In this study, researchers observed that platelet-rich plasma-derived exosomes significantly promoted hair regeneration in a murine model of alopecia by enhancing hair follicle stem cell activities and modulating the SIRT1/FoxO3a pathway, suggesting potential clinical benefits for alopecia treatment.

This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.

In this study, ritlecitinib treatment for 12 and 24 weeks downregulated immunity-related genes and upregulated hair keratin genes in patients with alopecia areata, correlating with scalp hair regrowth response.

This observational study found that while 96.6% of patients using valproic acid showed the expected clinical response, over half experienced adverse reactions like weight gain, hair loss, and hepatotoxicity, highlighting the need for personalized treatment approaches to minimize these side effects.

This study found that senior dogs fed amino acid-complexed and lysine-glutamic acid-complexed trace minerals had longer, faster-growing hair and increased activity compared to those fed inorganic trace minerals.

This review discusses the role of nanocarrier systems, such as nanoemulsions and liposomes, in delivering antioxidants into the skin to counteract oxidative stress, highlighting recent advancements in topical antioxidant therapy through nanotechnology.

This study highlights a close link between metabolic syndrome, characterized by conditions like obesity and hypertension, and various inflammatory skin diseases, suggesting that mitochondrial dysfunction plays a key role in their pathogenesis and could be a target for new therapies.

This review discusses the potential of P. polyphylla saponins to treat acne through antibacterial, anti-inflammatory, immunomodulatory, and antioxidant effects, noting that acne's complex pathogenesis makes this line of research promising for future studies.

This review summarizes current literature associating mitochondrial dysfunction with dermatologic issues like skin aging, hair loss, and poor wound healing, noting potential benefits in targeting mitochondrial components for treatments.

In this study, researchers found that Derinat, a TRPCs inhibitor, reduced oxidative stress and prolonged the anagen phase of hair growth in mice, supporting its potential as a therapy for androgenetic alopecia by improving clinical outcomes and enhancing quality of life for those affected.

This study developed a biocompatible hair-dyeing technology using a dark polyphenol complex, which demonstrated effective hair coating, improved mechanical strength, and strong antioxidant properties while maintaining high cell viability.

This review compiles existing research on infrared radiation's effects on human skin, noting both its potential harmful thermal impacts and encouraging therapeutic applications, but reports no new clinical results.

This study by Gao et al. reports that two nonsteroidal selective androgen receptor modulators, S1 and S4, demonstrated tissue-selective actions in rats, suppressing prostate growth while maintaining muscle growth without altering hormone levels.

This study suggests that the susceptibility of hair follicle melanocytes to oxidative stress as they age may be key in the graying of hair due to reduced catalase expression and activity.