June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that anabolic steroid use combined with plakoglobin deficiency caused pathological atrial electrical remodeling in young male mice, suggesting a higher risk of atrial myopathy for males with desmosomal gene variants.
May 2022 in “Indian Journal of Pharmacology” This case report highlights a rare instance of valproate-induced hypertensive urgency in a 2-year-old girl, with improvement after stopping the medication.
May 2021 in “American journal of medical sciences and medicine” This study observed that vomiting was the most frequent side effect of sodium valproate in children under two years old, with anemia, hair loss, and appetite loss being less common.
July 2020 in “Scholars journal of applied medical sciences” This study found that vomiting was the most common side effect of sodium valproate in children under two with epilepsy.
January 2019 in “Pediatric Oncall” This article reviews the use of valproate in epilepsy treatment and its side effects, noting that hair texture changes such as curly hair are a rarely reported effect, but reports no new clinical results.
September 2018 in “Practical diabetes” This review indicates that sodium valproate might benefit diabetic peripheral neuropathy patients, but evidence is limited and inconsistent, so it should be reserved for treatment-resistant cases.
August 2018 in “Online journal of neurology and brain disorders” This study reported that sodium valproate completely stopped epilepsy in 43% of patients and reduced seizures by 50% in 22% of patients who were resistant to other anticonvulsants.
May 2018 in “Dermatologic Surgery” This overview highlights the Dermatologic Surgery journal's comprehensive coverage of dermatologic surgical procedures, but it reports no new research findings.
This study concluded that a shampoo with 10% sodium lauryl sulfate showed the best physical properties among the tested formulas, aligning closely with the Indonesian National Standard.
January 2012 in “Journal of Cosmetics Dermatological Sciences and Applications” This study found that iontophoresis significantly enhances the skin penetration of magnesium salt of L-ascorbic acid 2-phosphate, especially in hairy mice, compared to passive diffusion.
January 2020 in “International journal of scientific and research publications” This article discusses androgenetic alopecia's mechanisms but reports no new study results.
19 citations
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April 2011 in “Headache The Journal of Head and Face Pain” This study found that both topiramate and divalproex sodium were similarly effective in reducing headache frequency by over 50% among episodic migraine patients after three months of treatment.
18 citations
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June 2016 in “PeerJ” In this study, testosterone increased the expression of epithelial sodium channel proteins and mRNAs in rat kidneys, suggesting a potential mechanism for its effect on blood pressure through enhanced sodium reabsorption.
16 citations
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October 1994 in “PubMed” This review, drawing on literature and personal experience, suggests that sodium valproate is a safe and effective antiepileptic drug for various epileptic conditions in children and adults, including the elderly.
10 citations
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September 2008 in “Andrologia” In this study, treatment with finasteride altered the expression patterns of antioxidant enzymes in the epididymis of rats, potentially affecting its protective function for spermatozoa.
7 citations
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January 2020 in “Skin Pharmacology and Physiology” In this study using ex vivo porcine ear skin, researchers found that standard nail varnish applied gently creates effective follicular closures, preventing penetration of certain substances like fluorescein sodium salt and caffeine into hair follicles, whereas solvent-free varnish and rapid application techniques were less effective.
3 citations
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March 2005 in “Journal of the American Academy of Dermatology” This case report describes a patient with Birt-Hogg-Dube syndrome exhibiting multiple fibrofolliculomas, acrochordons, and renal oncocytoma.
2 citations
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September 2023 in “JAAD Case Reports” This article discusses the chronic inflammatory skin diseases acne keloidalis nuchae and dissecting cellulitis of the scalp, focusing on their shared etiology and differing progression, and reports no new clinical findings.
1 citations
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January 2018 in “International Journal of Pharmaceutical Sciences and Drug Research” This study describes the development of a minoxidil gel using the copolymer Sepineo P 600, showing improved spreadability, occlusivity, adhesiveness, and stability compared to minoxidil lotion, without causing skin corrosion, making it a potentially more effective treatment form for alopecia areata.
June 2023 in “SDÜ Tıp Fakültesi Dergisi” This study found that long-term exposure to sodium valproate can increase oxidative stress and inflammation in rat stomach tissues, while treatment with rutin, a natural antioxidant, was associated with reduced markers of these effects at dosages of 50 mg/kg and 100 mg/kg.
January 2026 in “International Journal of Biological Macromolecules” The hydrogel improves hair growth treatment by enhancing drug delivery and promoting follicle repair.
August 2025 in “Journal of Cosmetic Dermatology” In this study, a DMG-Na and caffeine-containing shampoo significantly reduced hair loss and increased hair density in men with male pattern hair loss over 6 months, compared to a placebo, without adverse effects.
April 2025 in “Digital Commons - East Tennessee State University (East Tennessee State University)” In a mice model of atopic dermatitis, this study reported that a formulated cromolyn sodium oleate gel significantly reduced scab size and provided better healing than dexamethasone, with fewer adverse effects.
January 2021 in “International Journal of Advanced Research in Medicine” This study observed that propranolol, flunarizine, and divalproex sodium were equally effective in managing migraine across a three-month period in a group of 84 patients, with various side effects noted among the drug groups.
March 2016 in “The Korean Society of Beauty and Art” This study found that using a hair-hardener improved hair thickness, amino acid content, surface condition, tensile strength, and wave efficiency without causing any allergic reactions in participants.
This study found that both levetiracetam and valproate sodium effectively reduced seizure frequency and duration in patients with refractory epilepsy, but levetiracetam had fewer side effects related to liver enzyme changes.
January 2023 in “The Egyptian Journal of Hospital Medicine” This study found that topical valproic acid and 5% minoxidil both significantly increased hair count in patients with female pattern hair loss, suggesting topical valproic acid as a potential treatment option.
18 citations
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January 2009 in “Acta neurologica Scandinavica” In this study, the side effects of long-term sodium valproate treatment for refractory epilepsy were generally slight and transient, with severe side effects not observed.
1 citations
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October 2023 in “Journal of clinical psychopharmacology” In this case report, a young male developed bilateral pleural effusion and persistent fever after starting divalproex sodium for bipolar disorder, which improved upon discontinuation of the drug, suggesting a possible link between divalproex sodium and pleural effusion.
January 2025 in “Journal of Medical Biochemistry” This review explores the roles of superoxide dismutases in cellular processes and cancer, highlighting the potential of SOD mimetics in enhancing cancer treatment strategies, but it reports no new clinical findings.