106 citations
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December 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
610 citations
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April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
102 citations
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January 2018 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Restoring hair bulb immune privilege is crucial for managing alopecia areata.
54 citations
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November 2017 in “Scientific Reports” The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
92 citations
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August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
22 citations
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May 2021 in “Nature Communications” Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
16 citations
,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
11 citations
,
July 2017 in “Expert Opinion on Investigational Drugs” New hair loss treatments may include topical medications, injections, and improved transplant methods.
1 citations
,
November 2016 in “Congenital Anomalies” Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.
January 2019 Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
76 citations
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October 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
66 citations
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May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
57 citations
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March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
25 citations
,
September 2014 in “Biological Research” Arctiin helps protect hair cells from damage and death caused by oxidative stress.
14 citations
,
October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
5 citations
,
March 2015 in “Methods” The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
June 2019 in “International journal of dermatology and venereology” The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
55 citations
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December 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
25 citations
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July 2022 in “Developmental cell” Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
15 citations
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February 2021 in “Frontiers in immunology” Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
8 citations
,
March 2015 in “Molecular Medicine Reports” Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.
1 citations
,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
May 2023 in “Experimental Dermatology” 1 citations
,
December 2022 in “IntechOpen eBooks” Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
May 2022 in “Cardiovascular Toxicology” 17 citations
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January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
1 citations
,
May 2009 in “Wiley-Blackwell eBooks” Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.
4 citations
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October 2022 in “Genes” Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.
2 citations
,
April 2022 in “Clinical, cosmetic and investigational dermatology” A new plant-based treatment was effective for hair regrowth in women with a specific type of hair loss that didn't respond to usual treatments.