research Design, Synthesis, and Biological Evaluation of Novel Androst-3,5-Diene-3-Carboxylic Acid Derivatives as Inhibitors of 5α-Reductase Type 1 and 2
New chemical compounds were made that effectively block an enzyme linked to prostate growth.
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900-930 / 1000+ resultsresearch The Multipotency of Adult Vibrissa Follicle Stem Cells
Adult vibrissa follicle stem cells can regenerate hair follicles, glands, and skin.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Caspases in Life and Death: Their Role in Head Formation
Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
research Safflower Oil Body Nanoparticles Deliver hFGF10 to Hair Follicles and Reduce Microinflammation to Accelerate Hair Regeneration in Androgenetic Alopecia
Safflower oil nanoparticles can deliver hFGF10 to hair follicles, reduce inflammation, and potentially speed up hair growth in conditions causing hair loss.
research Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis
Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
research Qiviut Cortisol Reflects Hypothalamic–Pituitary–Adrenal Axis Activity in Muskoxen (Ovibos Moschatus)
Muskoxen's qiviut cortisol levels indicate their stress hormone activity over the hair growth period.
research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis
Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
research GDNF Promotes Hair Formation and Cutaneous Wound Healing by Targeting Bulge Stem Cells
GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
research Histological and Gene Expression Analysis of the Effects of Menopause Status and Hormone Therapy on the Vaginal Introitus and Labia Majora
Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.
research Ectopic Expression of FGF5s Induces Wool Growth in Chinese Merino Sheep
Overexpression of FGF5s makes Chinese Merino sheep grow longer and heavier wool.
research Effects of Neonatal and Adolescent Neuroactive Steroid Manipulation on Locomotor Activity Induced by Ethanol in Male Wistar Rats
Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.
research Industrial-Scale Processing of Activated Platelet-Rich Plasma from Specific Pathogen-Free Pigs and Its Effect on Promoting Human Hair Follicle Dermal Papilla Cell Cultivation
Pig blood plasma can be used to promote human hair growth and is a good alternative to the commonly used serum additive.
research Method for Chronological Recording of Antigen Appearance in Human Head-Hair Shafts and Its Use for Monitoring Glycation Products in Diabetes
The method can help diagnose and monitor diabetes by analyzing hair.
research Photodegradation of Human Hair: A Microscopy Study
UV radiation significantly damages hair, especially with humidity, making it more vulnerable to further damage.
research Jieduquyuziyin Prescription Alleviates SLE Complicated by Atherosclerosis via Promoting Cholesterol Efflux and Suppressing TLR9/MyD88 Activation
Jieduquyuziyin prescription helps treat SLE with atherosclerosis by improving cholesterol removal and reducing inflammation.
research Novel PLCL Nanofibrous/Keratin Hydrogel Bilayer Wound Dressing for Skin Wound Repair
The new wound dressing promotes cell growth and healing, absorbs wound fluids well, and is biocompatible.
research Research on Hair Removal Algorithm of Dermatoscopic Images Using Maximum Variance Fuzzy Clustering and Optimized Criminisi Algorithm
The new hair removal algorithm for skin images works better for detecting and fixing hair, improving melanoma diagnosis.
research Oral Delivery of Marine Shellfish Supramolecule Peptides for Skin Wound Healing
Eating peptides from certain shellfish may help wounds heal faster by reducing inflammation.
research Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Genome-Wide Identification, Characterization, and Expression Analysis of Keratin Genes (KRTs) Family in Yak (Bos Grunniens)
Scientists found 53 keratin genes in yaks that are important for hair growth and share similarities with those in other animals.
research Ethnobotany, Phytochemistry, Pharmacology, and Conservation of the Genus Calanthe R. Br. (Orchidaceae)
Calanthe orchids have medicinal potential and contain 265 chemical compounds, but are underexplored.
research Three Months Extended-Release Microspheres Prepared by Multi-Microchannel Microfluidics in Beagle Dog Models
A new device, IVL-PPF Microsphere®, was created to deliver a hair loss drug for up to 3 months with one injection, potentially replacing daily pills.
research Biomechanics of Hair Fiber Growth: A Multi-Scale Modeling Approach
The model shows that factors like follicle shape and stiffness are key for hair growth and anchoring.
research Comparative Characterization and Osteogenic/Adipogenic Differentiation of Mesenchymal Stem Cells Derived from Male Rat Hair Follicles and Bone Marrow
Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.
research Testosterone Enhances Expression and Functional Activity of Epithelial Sodium Channel, Cystic Fibrosis Transmembrane Regulator, and Sodium Hydrogen Exchanger in Vas Deferens of Sex-Steroid Deficient Male Rats
Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.
research Sensory and Physiological Dimensions of Cold Pressor Pain in Trichotillomania
Adults with trichotillomania do not have different pain sensitivity to cold pressor pain compared to healthy individuals.
research Mathematical Model for Alopecia Areata
The model showed that immune system guardians and the cytokine interferon-γ are key in alopecia areata progression.
research A Review on Ethnopharmacology, Phytochemistry, Pharmacology and Potential Uses of Portulaca Oleracea L.
Purslane has many health benefits and potential uses in medicine, food, and farming.
research Homogeneous Silver Nanoparticle Loaded Polydopamine/Polyethyleneimine-Coated Bacterial Cellulose Nanofibers for Wound Dressing
The new wound dressing material speeds up healing, fights infection, and outperforms traditional dressings.