Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.
238 citations,
April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
4 citations,
February 2022 in “International Journal of Molecular Sciences” Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.
154 citations,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
25 citations,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
1 citations,
August 2023 in “International Journal of Molecular Sciences” Platelet Rich Plasma-Derived Extracellular Vesicles show promise for healing and regeneration but need standardized methods for consistent results.
3 citations,
February 2021 in “FEBS open bio” Camellia japonica extract may improve scalp health and promote hair growth.
31 citations,
August 1975 in “Journal of Pharmaceutical Sciences” Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
728 citations,
August 1996 in “The New England Journal of Medicine” Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.
37 citations,
April 1979 in “The Journal of Clinical Pharmacology” Minoxidil effectively controls blood pressure but side effects may limit its use.
13 citations,
May 2011 in “Bioorganic & Medicinal Chemistry” Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
397 citations,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
74 citations,
July 1991 in “The Journal of Urology” Minoxidil works better than nitroglycerin for treating impotence with fewer side effects.
46 citations,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
36 citations,
January 2014 in “Elsevier eBooks” The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
33 citations,
April 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
29 citations,
December 2003 in “Teratology” Minoxidil use during pregnancy may cause fetal harm.
2 citations,
March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
2 citations,
April 2016 in “The Journal of Urology” Finasteride 1mg linked to diverse symptoms; other treatments improve erectile function in rats.
1 citations,
January 2010 in “Journal of Oriental Medicine” Black bean, wheat, and rice bran extracts can boost hair growth and improve hair quality.
January 2021 in “Pediatric Oncall” Autoimmune hepatitis in children often affects girls and can be treated successfully with medication.
January 2018 in “Elsevier eBooks” Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.
November 2015 in “European journal of dermatology/EJD. European journal of dermatology” A 55-year-old woman with several health conditions did not see hair regrowth after a transplant.
May 2016 in “The Journal of Sexual Medicine” 19 citations,
November 2018 in “Experimental Dermatology” The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
18 citations,
January 2017 in “Dermatologic Surgery” Combining cosmetic procedures with lifestyle changes improves antiaging results.
12 citations,
February 2010 in “Tetrahedron Letters” New minoxidil compounds with better water solubility were made, but their full effects and safety need more research.