research Deciphering the Molecular Mechanisms of Stem Cell Dynamics in Hair Follicle Regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
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60-90 / 1000+ results research Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression
Patched1 helps prevent tumors by controlling cell growth.
research Skin Stem Cells, Their Niche, and Tissue Engineering Approach for Skin Regeneration
Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock
BMAL1 and Period1 genes can influence human hair growth.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research An ERK-Dependent Molecular Switch Antagonizes Fibrosis and Promotes Regeneration in Spiny Mice
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
research Metabolomics Reveals Metabolites Associated with Hair Follicle Cycle in Cashmere Goats
Metabolites and diet affect hair growth cycles in cashmere goats.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth
Blocking JAK-STAT signaling can lead to hair growth.
research Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Hair Physiology and Its Disorders
Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
research TGF-β Family Signaling in Stem Cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Circadian Clocks: From Stem Cells to Tissue Homeostasis and Regeneration
Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
research Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Functional Hair Follicle Regeneration: An Updated Review
Hair follicle regeneration possible, more research needed.
research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research Hair Follicle Reconstruction and Stem Cells
Stem cells could improve hair growth and new treatments for baldness are being researched.
research Epidermal-Dermal Coupled Spheroids Are Important for Tissue Pattern Regeneration in Reconstituted Skin Explant Cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Hormonal Regulation and Systemic Signals of Skin Aging
Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
research Understanding the Functional Contribution of Dermal Stem Cells to Hair Follicle Regeneration and Skin Wound Healing
Dermal stem cells help regenerate hair follicles and heal skin wounds.
research Regeneration of Fat Cells from Myofibroblasts During Wound Healing
Some wound-healing cells can turn into fat cells around new hair growth in mice.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research The Harmonies Played by TGF-β in Stem Cell Biology
TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research Extraskeletal Actions of Vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.