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The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

The new wound dressing material speeds up healing, fights infection, and outperforms traditional dressings.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Mouse cell exosomes help hair regrowth and wound healing by activating a specific signaling pathway.

Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.

Fermenting Dendrobium officinale with Lactobacillus reuteri CCFM8631 increases its skin care benefits.

Eating fewer calories may slow skin aging and improve skin health through various biological changes.

Cellular and immunotherapies show promise for healing chronic wounds but need more research.

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.

Keratin from hair binds well to gold and BMP-2, useful for bone repair.

Skin organoids from stem cells could better mimic real skin but face challenges.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Intermediate filaments are crucial for cell differentiation and stem cell function.

ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.

Broussonetia papyrifera extract helps hair growth by regulating specific proteins.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Human pluripotent stem cells could be used to make platelets for medical use, but safety, effectiveness, and cost issues need to be resolved.

Exosomes could be a promising way to help repair skin and treat skin disorders.

Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.

Polyglutamic acid is a valuable, sustainable ingredient for skincare and haircare products.

Manipulating cell cleanup processes could help treat hair loss.

The CuCS/Cur wound dressing helps regenerate nerves and heal deep skin burns by rebuilding hair follicles.