research Drug Pipeline Q2 2022: A Downturn in Approvals
Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.
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research Eclipta Alba Extract With Potential For Hair Growth Promoting Activity
Eclipta alba extract may help hair grow similarly to Minoxidil.
research Design of a RADA16-Based Self-Assembling Peptide Nanofiber Scaffold for Biomedical Applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Resveratrol Derivatives: A Patent Review (2009–2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Spectrofluorimetric Study of Finasteride and Bovine Serum Albumin Interaction and Its Application for Quantitative Determination of Finasteride in Tablet Dosage Form
Method accurately measures finasteride in tablets using finasteride-BSA interaction.
research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity
Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.
research Screening of Synthetic and Natural Product Databases: Identification of Novel Androgens and Antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research Stability-Indicating Micellar Electrokinetic Chromatography Method for Determination of Finasteride in Pharmaceutical Preparations
Method accurately measures finasteride concentration in medicine.
research Structure-Guided Manipulation of the Regioselectivity of the Cyclosporine A Hydroxylase CYP-sb21 from Sebekia Benihana
Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.
research Bioactive Citrate-Based Polyurethane Tissue Adhesive For Fast Sealing And Promoted Wound Healing
The new adhesive seals wounds quickly, works well in wet conditions, and helps with healing.
research A Review on Tectona Grandis
Teak is a durable, termite-resistant wood with medicinal benefits.
research Computational Screening of Repurposed Drugs and Natural Products Against SARS-CoV-2 Main Protease as Potential COVID-19 Therapies
Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research The Cutaneous Serotoninergic/Melatoninergic System: Securing a Place Under the Sun
Human skin can make serotonin and melatonin, which help protect and maintain it.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review
Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
research Cepharanthine: An Update of Its Mode of Action, Pharmacological Properties, and Medical Applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata
Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.
research Application of Multiphoton Microscopy in Dermatological Studies: A Mini-Review
Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
research Polymeric Nanoparticles-Embedded Organogel for Roxithromycin Delivery to Hair Follicles
Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
research Potential of Nano-Phytochemicals in Cervical Cancer Therapy
Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research In Silico Prediction of Prostaglandin D2 Synthase Inhibitors from Herbal Constituents for the Treatment of Hair Loss
Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research The Effects of Particle Properties on Nanoparticle Drug Retention and Release in Dynamic Minoxidil Foams
Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.