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Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

A form of vitamin E promotes hair growth by activating a specific skin pathway.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

A specific RNA can help hair growth in baldness by boosting stem cell activity.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

Vitamin A affects hair loss and immune response in alopecia areata.

WWP2 is crucial for tooth development in mice.

Egyptian researchers are advancing in pharmaceutical nanotechnology, potentially improving health outcomes and the economy.

Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.

Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

Cholesterol-modified siRNAs targeting certain genes increased hair growth in mice.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Vitamin D boosts a specific protein in skin cells linked to hair follicles.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.