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5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis

research 5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis

15 citations, October 2014 in “Hormone Molecular Biology and Clinical Investigation”

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

research Lupus Erythematosus: Considerations About Clinical, Cutaneous, and Therapeutic Aspects

15 citations, January 2014 in “Anais Brasileiros de Dermatologia”

Lupus treatment requires a combination of drugs and therapies, with research needed for new options.

Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp

research Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp

14 citations, October 2020 in “Scientific reports”

Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.

research Promoting Axonal Regeneration Through Exosomes: An Update of Recent Findings on Exosomal PTEN and mTOR Modifiers

14 citations, October 2018 in “Brain Research Bulletin”

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways

research Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways

14 citations, June 2018 in “Frontiers in pharmacology”

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.

research Tooth, Hair, and Claw: Comparing Epithelial Stem Cell Niches of Ectodermal Appendages

14 citations, February 2014 in “Experimental Cell Research”

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis

research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis

14 citations, May 2013 in “American Journal of Physiology-endocrinology and Metabolism”

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

research Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying

13 citations, May 2022 in “Cell discovery”

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

research Perforin Expression by Cutaneous Gamma Delta T Cells

13 citations, August 2020 in “Frontiers in Immunology”

Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.

Comparison Between Single- Versus Double-Spin Prepared Platelet-Rich Plasma Injection in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor

research Comparison Between Single- Versus Double-Spin Prepared Platelet-Rich Plasma Injection in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor

10 citations, September 2020 in “Archives of Dermatological Research”

Both methods improve hair density and thickness; double-spin may be more effective.

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