37 citations
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May 2006 in “Regulatory Peptides” Mice skin has components that could help with hair growth and might be used for diabetes treatment.
26 citations
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February 1998 in “Chemico-Biological Interactions” Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.
14 citations
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September 2012 in “Archives of Dermatological Research” Phyto-vesicles of β-sitosterol may effectively treat hair loss.
4 citations
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July 2015 in “Journal of Feline Medicine and Surgery Open Reports” A cat with hair loss and illness was found to have cancer spread from its colon.
4 citations
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January 2015 in “Hair therapy & transplantation” Hair follicle stem cells could be used to treat the skin condition vitiligo.
2 citations
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.
2 citations
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January 2017 in “Clinical and medical investigations” Herbal lotions are effective for severe hair loss, with a 64.8% success rate, but relapse is common and long-term management requires allergen control and possible corticosteroid use.
1 citations
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November 2017 The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
610 citations
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April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
551 citations
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November 2013 in “Nature” Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
403 citations
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January 2019 in “Cell stem cell” Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
160 citations
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June 2012 in “Journal of Cellular and Molecular Medicine” Telocytes might help with skin repair and regeneration.
156 citations
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November 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
139 citations
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November 2015 in “Journal of Advanced Research” Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
71 citations
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January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
69 citations
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September 1991 in “Journal of Surgical Research” Understanding how fetal wounds heal could help improve healing in adults.
61 citations
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May 2016 in “Scientific reports” The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.
47 citations
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July 2005 in “British Journal of Dermatology” Topical vitamin D3 does not prevent hair loss from chemotherapy.
43 citations
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October 1955 in “The journal of nutrition/The Journal of nutrition” Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.
42 citations
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June 2021 in “Journal of clinical pharmacology” Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
36 citations
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December 2015 in “Drugs” New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.
34 citations
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June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
33 citations
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September 2017 in “Journal of clinical immunology” New treatments for immune disorders caused by FOXN1 deficiency are promising.
32 citations
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July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
30 citations
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October 2016 in “Advances in radiation oncology” Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
24 citations
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July 2018 in “Stem cells” Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
23 citations
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December 2015 in “Anais Brasileiros de Dermatologia” Permanent hair loss after bone marrow transplant can be caused by chemotherapy or chronic graft-versus-host disease.
19 citations
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July 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
11 citations
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January 2016 in “Journal of clinical & experimental dermatology research” Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.
9 citations
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January 2017 in “Virchows Archiv” LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.