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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Fat cells help recruit healing cells and build skin structure during wound healing.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The Rotterdam Study aims to understand various diseases in older adults.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Researchers created human hair follicles using a new method that could help treat hair loss.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

New effective scar treatments are urgently needed due to the current options' limited success.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Radiation therapy with a higher dose for the brain improves survival in cerebellar medulloblastoma.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.