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Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

A new one-step test can quickly identify skin cancer during surgery.

Topical glucocorticoids thin the skin and change collagen structure.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

New insights into cell communication in psoriasis suggest innovative drug treatments.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

Effective PCOS treatments require targeting specific signaling pathways.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

Minoxidil might help treat acne scars by reducing collagen buildup.

Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

Scalp psoriasis can cause different types of hair loss, with some patients developing permanent hair loss, and treatment may be stopped due to skin reactions.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Cholecystokinin may help reduce skin inflammation in psoriasis.

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.

Higher leptin levels link to hair loss.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.

P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.

Genes affecting wool fiber thickness in Angora rabbits were identified, which could help breed finer wool.

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.

Angiogenin may help treat hair loss by reducing certain proteins in hair cells.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.