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    Glossary SM04554

    investigational drug studied for treating androgenetic alopecia

    SM04554 is an investigational drug being studied for its potential to treat androgenetic alopecia, a common form of hair loss. It is believed to work by modulating the Wnt signaling pathway, which plays a crucial role in hair follicle development and growth.

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    Research 30 of 43

    1. Safety and efficacy of a topical treatment (SM04554) for androgenetic alopecia (AGA): Results from a phase 1 Trial Journal of The American Academy of Dermatology · 2016 · 2 citations
    2. Safety and biopsy outcomes of a topical treatment (SM04554) for male androgenetic alopecia (AGA): Results from a phase 2, multicenter, randomized, double-blind, vehicle-controlled trial Journal of The American Academy of Dermatology · 2017 · 1 citations
    3. 712 A small molecule modulator of the wnt pathway (SM04554) as a potential topical treatment for androgenetic alopecia (AGA) Journal of Investigative Dermatology · 2017 · 1 citations
    4. WNT Signaling in Disease Cells · 2019 · 144 citations
    5. New drugs under investigation for the treatment of alopecias Expert Opinion on Investigational Drugs · 2019 · 26 citations
    6. Biotechs target stagnant baldness market Nature Biotechnology · 2016 · 3 citations
    7. Randomized controlled evaluator blinded study of dutasteride versus finasteride in men with androgenetic alopecia Journal of The American Academy of Dermatology · 2016 · 1 citations
    8. New Drugs for Alopecias 2019
    9. Safety and efficacy of a novel skin lightening agent for melasma Journal of The American Academy of Dermatology · 2017
    10. Safety and compatibility of a new nourishing baby shampoo and tip to toe wash with stearic acid Journal of The American Academy of Dermatology · 2017
    11. Safety and efficacy of actinic keratoses reduction with a 3 day application of ingenol disoxate field treatment to the face, chest and balding scalp Journal of The American Academy of Dermatology · 2017
    12. 710 Use of mass spectrometry imaging and a full thickness 3D skin equivalent for evaluation of percutaneous absorption Journal of Investigative Dermatology · 2017
    13. Relapsing nail fibrokeratoma: A case report on a teenager Journal of The American Academy of Dermatology · 2016
    14. Recent updates on Wnt signaling modulators: a patent review (2014-2020) Expert Opinion on Therapeutic Patents · 2021 · 14 citations
    15. Androgens and androgen receptor action in skin and hair follicles Molecular and Cellular Endocrinology · 2017 · 100 citations
    16. A review of the treatment of male pattern hair loss Expert Opinion on Pharmacotherapy · 2020 · 53 citations
    17. Novedades terapéuticas en tricología Actas Dermo-Sifiliográficas · 2017 · 20 citations
    18. Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options Expert Opinion on Therapeutic Targets · 2019 · 19 citations
    19. Experimental and early investigational drugs for androgenetic alopecia Expert Opinion on Investigational Drugs · 2017 · 11 citations
    20. New Treatments for Hair Loss Actas Dermo-Sifiliográficas · 2017 · 7 citations
    21. Clinical Trials and Hair Loss Elsevier eBooks · 2018 · 1 citations
    22. Alopesi Tedavisinde Kullanılan İlaç Tedavileri ve Yeni Yaklaşımlar 2025
    23. 713 Fisetin promotes differentiation, inhibits proliferative and inflammatory responses in cultured human cells and alleviates psoriasiform dermatitis in mice Journal of Investigative Dermatology · 2017
    24. 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment Journal of Investigative Dermatology · 2017
    25. 708 SIG-1451: A topical anti-inflammatory new chemical entity for atopic dermatitis (AD) Journal of Investigative Dermatology · 2017
    26. 709 Nitric oxide-releasing topical therapeutic agent for atopic dermatitis Journal of Investigative Dermatology · 2017
    27. withdrawn Journal of The American Academy of Dermatology · 2016
    28. Nouvelles thérapeutiques dans la prise en charge de l’alopécie androgénétique HAL (Le Centre pour la Communication Scientifique Directe) · 2025
    29. Wnt is back in drugmakers' sights, but is it druggable? Nature Biotechnology · 2018 · 10 citations
    30. Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture Molecules · 2022 · 7 citations