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This review discusses the potential uses, benefits, and challenges of solid lipid nanoparticles in drug delivery systems but presents no new experimental findings.

This study found that adding cell adhesion-linked gene expression variables improved the identification of patients with SLN metastases within 90 days of melanoma diagnosis compared to using clinicopathologic variables alone.

This study found that a lacticin 3147 solid lipid nanoparticle gel demonstrated potent and sustained antimicrobial activity against S. aureus, including MRSA, in ex vivo S. aureus-infected pig skin.

This study found that POD-loaded solid lipid nanoparticles using 0.5% poloxamer 188 and 1.5% soybean lecithin (P-SLN) improved epidermal targeting and POD accumulation in porcine skin compared to traditional tincture.

This study found that sub-100 nm size solid lipid nanoparticles showed the most effective skin penetration and depth, mainly via hair follicles, in rat skin.

This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.

This review discusses lipid nanoparticle-based cosmetics, emphasizing their potential in protecting skin from radiation and treating conditions like atopic dermatitis and psoriasis with synthetic and natural antioxidants. It highlights recent research on these formulations' effectiveness in alleviating skin disorders and enhancing skin health.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

This study found that the nanostructured lipid carrier formulation with a 70:30 solid to liquid lipid ratio significantly increased the dissolution rate, entrapment efficiency, and stability of spironolactone compared to its raw form.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

This study found that nanostructured lipid carriers enhanced the skin penetration and retention of minoxidil compared to solid lipid nanoparticles, suggesting they could be a promising method for topical delivery.

This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.

This study reports that RU 58841-myristate, a new antiandrogen prodrug formulated with solid lipid nanoparticles, shows potential for targeting hair follicles in preclinical laboratory settings.

This chapter reviews nanotechnology in cosmetics, detailing various formulations, performance assessment methods, and evolving regulations, while discussing safety, stability, and effectiveness concerns; it reports no new experimental results.

This study highlights that solid lipid nanoparticles may improve the absorption and bioavailability of poorly soluble drugs, offering advantages over conventional formulations for various administration routes.

This study developed solid lipid nanoparticles for effective delivery of shRNA-encoding plasmids, showing reduced 5α-reductase levels in DU-145 cells without significant cytotoxicity.

This study developed a caffeine-loaded solid lipid nanoparticle gel, observing significant reduction in subcutaneous fat tissue thickness in histological tests compared to an untreated group, suggesting it could effectively treat cellulite as a promising nanocosmeceutical gel.

This article reviews the promising ease of drug administration via transdermal and other topical routes, highlighting their potential for high patient compliance and reduced side effects but provides no new clinical results.

This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.

This review discusses the use of lipid nanoparticles for topical and transdermal delivery of pharmaceuticals and cosmeceuticals and reports no new clinical results.

This study found that ketoconazole-loaded solid lipid nanoparticles significantly improved skin permeation and retention compared to a drug suspension and marketed product, demonstrating enhanced delivery into deeper skin layers.

This letter to the editor reports that sentinel lymph node status is the strongest independent predictor for both disease-free and overall survival in patients with thick melanoma.

This study reported that solid lipid nanoparticles of finasteride decorated with chitosan enhanced drug retention in skin layers, suggesting potential application in treating androgenic alopecia and benign prostate hyperplasia with fewer side effects.

This study found that a fenugreek seed extract nanoformulation significantly improved hair growth and length in Wistar rats with alopecia, outperforming conventional gels and oils, suggesting enhanced skin penetration and reduced side effects.

This review provides a comprehensive examination of the causes and treatments for hirsutism in women, highlighting the role of pharmacological therapies and novel nanotechnology-based methods in improving patient quality of life.

This study reported that a solid lipid nanoparticle-based gel formulation, specifically optimized for psoriasis, improved drug loading capacity and release properties using high-pressure homogenization, suggesting its potential efficacy as a topical treatment.

This article reviews EU cosmetic product claim regulations and highlights increased harmonization and enforcement while reporting no new results.

This study found that a hair serum containing Acanthus ebracteatus extract improved hair regrowth in men with androgenic alopecia, increasing hair count and density of anagen hairs over a 6-month period, with combination treatments showing early effectiveness.

This study found that biotinoyl tripeptide-1-loaded solid lipid nanoparticles significantly improved thermal protection in hair, enhancing cuticle integrity and resistance to heat damage, compared to control samples.

In this study, BTP-loaded solid lipid nanoparticles were developed and shown to protect hair from heat-induced damage by enhancing cuticle integrity and thermal resistance in simulated thermal straightening conditions.