research Characterization of the Cysteine-Rich Calcium-Binding S100A3 Protein from Human Hair Cuticles
Scientists found out how a specific protein in human hair cuticles behaves and is structured.
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research Effect of Surfactant Type on the Dyeability and Color Resistance of Semi-Permanent Basic Hair Dye
Cationic and nonionic surfactants provide better color intensity and resistance for semi-permanent hair dye than anionic surfactants.
research A Methodological Exploration of Distinguishing Hair Quality Based on Hair Proteomics
Bleaching damages hair by reducing the quality of keratin and keratin-associated proteins.
research Transethosomes: A Comprehensive Review of Ultra-Deformable Vesicular Systems for Enhanced Transdermal Drug Delivery
The review provides a comprehensive analysis of transethosomes, ultra-deformable vesicular systems that enhance transdermal drug delivery by improving skin penetration, solubility, absorption, and stability of therapeutics. These systems combine the benefits of transferosomes and ethosomes, allowing for the encapsulation of both hydrophilic and hydrophobic drugs, and are applicable in various administration routes, including ophthalmic and transvaginal. Transethosomes have shown promise in treating conditions like psoriasis, skin cancer, and fungal infections, with studies demonstrating improved drug release and therapeutic efficacy. Despite challenges such as stability issues and potential skin irritation, transethosomes offer a versatile and scalable solution for enhanced drug delivery, with ongoing research exploring their broader applications beyond transdermal delivery.
research Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo
Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
research Dermal Nanocrystals from Medium Soluble Actives: Physical Stability and Stability Affecting Parameters
Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.
research The Structure of the Amorphous Matrix of Keratins
Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.
research Unchanged Androgen-Binding Properties of Sex Hormone-Binding Globulin in Male Patients with Liver Cirrhosis
SHBG binding properties are unchanged in male liver cirrhosis patients.
research Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
research WNT Signaling in the Control of Hair Growth and Structure
The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
research Cloning of a Functional Vitamin D Receptor from the Lamprey, an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth
Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21
A cluster of sulfur-rich hair protein genes was found on chromosome 17.
research Protection Against Chemotherapy-Induced Alopecia
No treatment fully prevents hair loss from chemotherapy yet.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Recent Advances in Nanocarrier-Loaded Gels: Which Drug Delivery Technologies Against Which Diseases?
Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
research A Discourse on Human Hair Fibers and Reflections on the Conservation of Drug Molecules
Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
research Phosphatidic Acid Has Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells
Phosphatidic acid may help hair grow by affecting cell growth pathways.
research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Transplantation of Bone-Marrow-Derived Mesenchymal and Epidermal Stem Cells Contribute to Wound Healing with Different Regenerative Features
Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
research Interventions for Female Pattern Hair Loss
Minoxidil effectively treats female pattern hair loss.
research Smad1 and Smad5 but Not Smad8 Establish Stem Cell Quiescence Critical for Transforming Premature Hair Follicles During Morphogenesis to the Postnatal State
Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 in a Growth- and Stress-Dependent Fashion
Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
research Phosphatidylinositol-Specific Phospholipase C2 Functions in Auxin-Modulated Root Development
A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.
research Update on Drugs Used to Treat Endocrine Diseases in Small Animals
New drugs are improving treatment for hormone-related diseases in small pets.
research Structures of Three Polycystic Kidney Disease-Like Domains from Clostridium Histolyticum Collagenases ColG and ColH
The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
research Engineering Cell-Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research CD133-Positive Dermal Papilla-Derived Wnt Ligands Regulate Postnatal Hair Growth
Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
research Effects of the Anti-Androgen Finasteride on 5-Alpha-Reductase Activity in Human Gingival Fibroblasts in Response to Minocycline
Finasteride helps treat hair loss by blocking enzyme activity.