This case study suggests that obstructive sleep apnea syndrome may be hereditary in patients with connective tissue disorders due to a variant in the COL1A2 gene.
April 2025 in “The Egyptian Journal of Surgery” This study found that the SASJ procedure is a safe and effective bariatric approach, resulting in significant weight loss, improvement in obesity-related comorbidities, and a low risk of postsurgical complications over one year.
March 2024 in “Cell communication and signaling” This study found that sleep deprivation in mice can trigger prostatitis by activating the cGAS-STING pathway due to reduced levels of dihydrotestosterone and melatonin, resulting in a pro-inflammatory environment, while recovery sleep can mitigate these effects.
February 2024 in “medRxiv (Cold Spring Harbor Laboratory)” This study aims to assess how daily life factors affect sleep patterns and describe individual sleep changes across the year, with results to be published in future research.
December 2023 in “Palestinian medical and pharmaceutical journal/Palestinian medical & pharmaceutical journal” The pilot study found that while women with habitual short sleep increased their sleep duration by an average of 40.7 minutes, there were no significant changes in insulin sensitivity, androgens, or leptin levels post-intervention, suggesting further research is needed.
March 2021 in “Journal of sleep sciences” This study found that patients with various types of alopecia had affected quality of life and sleep, but these factors were not significantly associated with demographic variables.
83 citations
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May 2011 in “Experimental Dermatology” In this study, researchers identified nine new sheep keratin genes, highlighting species-specific differences in the expression and compartmentalization of wool-related keratin genes compared to humans.
72 citations
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May 1993 in “The Journal of Cell Biology” This study detailed the structure and amino acid composition of sheep trichohyalin, noting its presence in various tissues and suggesting a possible functional role beyond structural support in hair follicles.
45 citations
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June 1984 in “Journal of the American Veterinary Medical Association” In this study, zinc supplementation rapidly improved conditions such as anorexia, depression, and foot soreness in sheep and goats diagnosed with zinc deficiency, along with healing skin lesions and resumption of hair and wool growth.
24 citations
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February 2016 in “Journal of Animal Physiology and Animal Nutrition” The researchers reported that the net mineral requirements for weight gain in Morada Nova lambs differ from commonly recommended values by the Agricultural and Food Research Council.
13 citations
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June 2024 in “BMC Genomics” This study found distinct expression patterns of various transcription types during hair follicle morphogenesis, providing a foundation for understanding hair development mechanisms and aiding selective breeding for desirable wool traits in a specific breed.
13 citations
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March 2012 in “The American Journal of Surgery” This study found that modified laparoscopic sleeve gastrectomy in patients with type 2 diabetes and obesity reduced ghrelin levels, improved glycemic and insulin levels, and resulted in significant weight loss.
4 citations
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December 2022 in “Al-mağallaẗ al-ʻirāqiyyaẗ li-l-ʻulūm al-bayṭariyyaẗ/Iraqi journal of veterinary sciences” This study conducted in Egypt evaluated antifungal treatments for sheep with dermatophytosis, finding that tioconazole cream, clotrimazole spray, and fluconazole capsules were effective, with tioconazole cream providing an easily applicable and highly effective topical option, achieving a 100% cure rate in the short term.
2 citations
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February 2025 in “PLoS ONE” This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.
2 citations
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November 2024 in “PeerJ” This study identified a wide range of differentially expressed lncRNAs and mRNAs in the hair follicles of Hetian sheep, which may be useful for further research on improving carpet wool quality.
2 citations
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January 2006 in “Indian Journal of Veterinary Pathology” In this study of sheep across various breeds and ages, researchers found that Trichophyton mentagrophytes caused severe dermatophytosis, especially affecting young Shahbadi sheep during winter, leading to notable anemia and skin lesions.
1 citations
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January 2023 in “Frontiers in genetics” This study identified specific genetic markers related to wool quality in Rambouillet sheep, which may aid breeders in making informed selection and breeding decisions for improved fine wool production.
1 citations
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January 2012 in “International journal of trichology” This study found that keratinocytes derived from the germinative epithelium of ovine hair follicles have extensive in vitro growth potential, challenging the idea that these cells are solely transit-amplifying.
1 citations
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January 1992 in “DNA sequence” This study found that a cuticle keratin gene in sheep is a pseudogene due to gene duplication and mutations, lacking expression in vivo.
June 2026 in “Food Science and Human Wellness” In this study, the high polarity fraction of Lanzhou Fat-Tailed Sheep tail fat showed significant antioxidant and wound healing properties in a mouse model, promoting faster wound closure and reducing inflammation by modulating cytokine levels and enhancing collagen production.
August 2025 in “Scientia Plena” In this study on sheep, researchers found that 10% Aloe vera extract had satisfactory healing effects on skin wounds, demonstrating effective macroscopic and partially differing microscopic results compared to control groups after 22 days of treatment.
January 2025 in “Open Veterinary Journal” This study found that sheep with deficiencies in zinc, copper, and vitamin A exhibited symptoms like weight loss, skin disorders, and abnormal hematological and antioxidant enzyme levels compared to healthy sheep, suggesting that dietary supplementation of these nutrients could prevent these health issues.
December 2024 in “Frontiers in Veterinary Science” This study on Dorper sheep identified important genetic factors influencing hair follicle development, finding that expression patterns and genes like DBI, FZD3, and ZDHHC21 play a crucial role in wool shedding, which could help improve understanding of mammalian skin-related traits and human hair advancement.
January 2024 in “Kafkas Universitesi Veteriner Fakultesi Dergisi” In this study, researchers found that oar-miR-377 regulates secondary hair follicle development in sheep by downregulating the SLC24A2 gene, and a specific SNP in oar-miR-377 is significantly associated with wool fiber diameter variation in Chinese Merino sheep.
May 2021 in “Veterinarìâ, tehnologìï tvarinnictva ta prirodokoristuvannâ” This study found 100% efficacy in treating psoroptosis in sheep and wild goats using macrolide injections "Iveron-10" and "Dectomax," complemented by "Butox-50" bathing in sheep, though infestation initially affected all animals with varied severity.
In this study of Swedish sheep herds, nutritional deficiencies and telogen effluvium, possibly due to cold stress after shearing, were suggested as primary causes of wool loss.
January 2009 in “Xumu shouyi xuebao” In this study, researchers successfully established a stable transgenic sheep fibroblast cell line containing an artificially synthesized spider dragline silk protein gene.
32 citations
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September 2010 in “Stress” This study found that suppressing allopregnanolone production in late gestation fetal sheep altered CNS activity and behavioral responses to transient asphyxia, effects mitigated by an analog co-infusion.
27 citations
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January 2017 in “Neuropsychopharmacology” This study found that acute sleep deprivation enhanced 5α-reductase expression and activity in the rat prefrontal cortex, and finasteride treatment reduced associated psychosis- and mania-like behaviors.
2 citations
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July 2025 in “Journal of Health Population and Nutrition” This study suggests that managing sleep disorders, particularly those involving difficulty initiating sleep, may benefit from dietary interventions that reduce proinflammatory nutrients and increase anti-inflammatory nutrients.