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Certain maturity signs appear before and after the first release of sperm in boys.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Rotterdam Study aims to understand various diseases in older adults.

Hair loss in men is common, treatable, but not curable.

Zinc is effective for treating various skin conditions, including warts and acne.

Male pattern baldness involves genetics, hormones, and needs better treatments.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Choosing the right recall period for patient feedback is important for accurate data and depends on the disease, symptom changes, and patient impact.

Certain genes control the color of human hair by affecting pigment production.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

New treatments for male hypogonadism are effective and should be personalized.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.