24 citations
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March 2007 in “International Journal of Dermatology” This study translated and culturally adapted the Skindex-16 questionnaire into Arabic, finding it to be a reliable and valid measure of quality-of-life impacts from skin diseases in Saudi patients.
17 citations
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July 2017 in “International Journal of Behavioral Medicine” This study validated the Egyptian Arabic version of the Skindex-16 and found that skin conditions significantly impacted patients' quality of life, particularly in the emotional domain.
June 2026 in “Value in Health” 
86 citations
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May 2011 in “Journal of The American Academy of Dermatology” This study found that patients with alopecia perceive their hair loss as more severe than dermatologists do, and their own ratings of hair loss severity better reflect their quality of life impacts.
52 citations
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March 2016 in “JAMA dermatology” This study found that hirsutism significantly negatively impacts quality of life, with self-assessed severity more strongly linked to quality-of-life impact and depressive symptoms than clinician assessments.
4 citations
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March 2023 in “SKIN The Journal of Cutaneous Medicine” This abstract does not provide specific results or a conclusion; additional context is needed to interpret the data.
January 2026 in “Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna)” This study observed that baricitinib led to significant hair regrowth and improved psychological well-being in severe alopecia areata patients over 48 weeks, with 63.2% achieving a SALT score of ≤20.
September 2025 in “Journal of the American Academy of Dermatology” Eyebrow and eyelash hair loss in alopecia areata worsens quality of life.
July 2025 in “Journal of Investigative Dermatology” This study found that high-dose UVA-1 therapy appeared to improve both patient-reported outcomes and objective clinical measures in patients with morphea and systemic sclerosis, supporting its potential efficacy for treating scleroderma.
November 2023 in “JEADV Clinical Practice” In this study, adults with severe alopecia areata experienced greater improvements in hair regrowth, health-related quality of life, and reduced anxiety and depression symptoms after 36 weeks of treatment with baricitinib compared to placebo.
August 2024 in “Frontiers in Public Health” In this study, researchers developed and tested an Italian version of the Skindex-16AA to assess Health-Related Quality of Life in patients with moderate-to-severe Alopecia Areata, emphasizing the importance of patient perception in evaluating their mental health and quality of life.
41 citations
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January 2012 in “Journal of Korean Medical Science” This study found a high prevalence of skin diseases, such as acne and tinea pedis, among Korean military personnel, highlighting their potential impact on soldiers' daily lives.
15 citations
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July 2021 in “JAMA Dermatology” This study found that androgenetic alopecia is significantly associated with moderate impairment of health-related quality of life and emotions, but not with depressive symptoms.
25 citations
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December 2015 in “Journal of the European Academy of Dermatology and Venereology” This study found that alopecia areata negatively affects patients' quality of life, though less severely than psoriasis, atopic dermatitis, and onychomycosis.
18 citations
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July 2016 in “British Journal of Dermatology” This review discusses patient-reported outcomes for health-related quality of life in cutaneous lupus erythematosus and reports no new clinical results; the authors note limited existing research and recommend further studies.
September 2016 in “Annals of occupational and environmental medicine” In this study, cleanroom workers in a secondary battery factory reported worse dermatologic life quality compared to non-cleanroom workers, as measured by the Skindex-29 questionnaire.
In this clinical trial, patients with lichen planopilaris treated with the oral TYK2 inhibitor deucravacitinib showed significant improvement in PGA, LPPAI, and Skindex-16 scores over 24 weeks, with transcriptomic analyses indicating decreased inflammatory and immune pathway activity post-treatment.
December 2013 in “Praxis medica” In this study, a strong correlation was found between the scores of two dermatology-specific quality of life instruments, DLQI and Skindex-16, suggesting they can provide complementary insights for assessing patients with skin diseases.
This study found that androgenic alopecia significantly impaired quality of life among men in the Eastern Province of Saudi Arabia, with younger males and those diagnosed by a doctor experiencing greater quality of life issues, particularly in the symptoms domain.
April 2016 in “Journal of The American Academy of Dermatology” AGA patients have a lower quality of life than AA patients.
August 2026 in “Russian Journal of Skin and Venereal Diseases” In this prospective study, combining photodynamic therapy with PRP therapy significantly improved hair growth, quality of hair, and quality of life in women with acute telogen effluvium, compared to using each therapy alone.
17 citations
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June 2024 in “Journal of the European Academy of Dermatology and Venereology” This study suggests that using an appropriate tool for measuring quality of life is vital, particularly as factors like severity, female sex, and eyebrow involvement may increase the psychosocial burden of alopecia areata.
November 2025 in “Journal of Clinical Medicine” The researchers reported that baricitinib treatment for at least 52 weeks reduced severe alopecia areata severity and improved psychological well-being and quality of life in study participants.
September 2025 in “Journal of the European Academy of Dermatology and Venereology” This real-world study found that baricitinib 4 mg daily was effective in promoting hair regrowth and improving psychological well-being in Italian adults with severe alopecia areata over 48 weeks, with 63.2% of patients achieving significant hair recovery and 9.4% experiencing adverse events.
9 citations
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January 2014 in “Postepy Dermatologii I Alergologii” This study evaluated the Polish version of Skindex-29, demonstrating its reliability and validity as a tool to measure quality of life in dermatology patients.
August 2019 in “Journal of The American Academy of Dermatology” RV3466F lotion significantly reduces hair loss and improves acute telogen effluvium.
13 citations
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January 2018 in “Annals of Dermatology” Alopecia areata and androgenetic alopecia affect quality of life similarly.
9 citations
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March 2018 in “Actas Dermo-Sifiliográficas” This study found that the Spanish version of the Hair Specific Skindex 29 (HSS29) is a reliable and valid tool for assessing the quality of life impact of female androgenetic alopecia.
1 citations
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November 2019 in “Actas Dermo-Sifiliográficas” This study found that the Spanish version of the hair-specific Skindex-29 questionnaire effectively detected changes in health-related quality of life among women with female-pattern hair loss, and the scores were significantly correlated with the SF-12 survey results after treatment with a 5 alpha-reductase inhibitor.
May 2018 in “Actas Dermo-Sifiliográficas” This study validated a Spanish version of the Hair Specific Skindex 29 scale for assessing quality of life in women with female androgenetic alopecia, showing similar psychometric properties to the original.