research Organoids in Skin Wound Healing
Skin organoids help improve wound healing and tissue repair.
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research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
research Fzd2 Controls Multiple Aspects of Epidermal Development Through Distinct Signaling Mechanisms
Fzd2 is important for skin and hair development through various signaling ways.
research A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth
Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
research What's New in Dermatological Research?
2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
research Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
Controlled light treatment in mouse skin speeds up healing and hair growth.
research Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile
Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.
research Aberrant Wnt Signaling Induces Comedo-Like Changes in the Murine Upper Hair Follicle
Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
research Reflections on How Wound Healing-Promoting Effects of the Hair Follicle Can Be Translated into Clinical Practice
Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
research Extracellular Fraction of Adipose Tissue as an Innovative Regenerative Approach for Vitiligo Treatment
Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.
research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders
Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
research P63 Targeted Deletion Under the FOXN1 Promoter Disrupts Pre- and Post-Natal Thymus Development, Function, and Maintenance, and Induces Severe Hair Loss
Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
research Stem Cell Dynamics in the Hair Follicle Niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts
Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
research Ostrich Antibody and Its Application to Skin Diseases: A Review and Case Report
Ostrich antibodies are a promising, cost-effective treatment for various skin diseases and conditions.
research Dermal Adipose Tissue Has High Plasticity And Undergoes Reversible Dedifferentiation In Mice
Dermal adipose tissue in mice can change and revert to help with skin health.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Intravital Imaging of Hair Follicle Regeneration in the Mouse
Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice
Only skin melanocytes, not other types, can color hair in mice.
research Stem-Cell Therapy in Dermatology: Challenges and Opportunities
Stem-cell therapy shows promise for skin conditions but needs more research.
research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research The Notch Intracellular Domain Has an RBPj-Independent Role During Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research Thymic Stromal Lymphopoietin Controls Hair Growth
Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
research Stretching the Limits: From Homeostasis to Stem Cell Plasticity in Wound Healing and Cancer
Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
research The Use of Polyethylenimine–DNA to Topically Deliver hTERT to Promote Hair Growth
Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
research Comparative Biology of Tissue Repair, Regeneration, and Aging
The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
research Future Horizons in Hair Restoration
New cell-based therapies may improve hair loss treatments in the future.
research Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair
The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
research Bullous Pilomatrixoma: Without a Shadow of Doubt – Role of ROSE and Cytology
Fine needle aspiration with rapid on-site evaluation is useful for diagnosing pilomatrixoma.