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    Glossary Skin-derived Precursors

    stem cells from skin that can become various cell types

    Skin-derived Precursors (SKPs) are a type of stem cell found in the dermis layer of the skin. These cells have the ability to differentiate into various cell types, including neurons, glial cells, and smooth muscle cells, making them valuable for regenerative medicine and tissue engineering.

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    1. Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors Stem Cells Translational Medicine · 2016 · 44 citations
    2. Induction of Skin-Derived Precursor Cells from Human Induced Pluripotent Stem Cells PLOS ONE · 2016 · 21 citations
    3. TSA restores hair follicle-inductive capacity of skin-derived precursors Scientific Reports · 2019 · 18 citations
    4. Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors Stem cells translational medicine · 2016 · 17 citations
    5. Isolation and Cultivation of Skin-Derived Precursors Methods in molecular biology · 2018 · 3 citations
    6. Defining The Role of Primary Cilia on Skin Derived Precursors. Journal of undergraduate research in Alberta · 2012
    7. Hair follicle dermal stem cells and skin‐derived precursor cells: Exciting tools for endogenous and exogenous therapies Experimental Dermatology · 2017 · 30 citations
    8. Generating Skin‐Derived Precursor‐Like Cells From Human‐Induced Pluripotent Stem Cell‐Derived Skin Organoids Experimental Dermatology · 2024
    9. 891 Comparison of phenotypes and transcriptomes of mouse skin-derived precursors and dermal mesenchymal stem cells Journal of Investigative Dermatology · 2019
    10. Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34+ Precursor Cells Enhances Healing with Hair Follicle Regeneration Advances in wound care · 2019 · 2 citations
    11. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009 · 330 citations
    12. Tendon dECM Composited with Chitosan with Loading Skin Precursor Stem Cell Exosome for Enhanced Diabetic Wound Healing Gels · 2026
    13. Engineered Skin Substitute Regenerates the Skin with Hair Follicle Formation Biomedicines · 2021 · 5 citations
    14. Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin Elsevier eBooks · 2018 · 1 citations
    15. 3D bioprinting of prefabricated artificial skin with multicomponent hydrogel for skin and hair follicle regeneration Theranostics · 2025
    16. 692 Study of the impact of SKPs’ secreted factors and of a botanical extract derived from jasmine on keratinocytes growth and reconstructed human epidermis thickness Journal of Investigative Dermatology · 2016
    17. Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin Nature Immunology · 2012 · 286 citations
    18. Skin tissue engineering Stembook · 2009 · 12 citations
    19. Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal npj Regenerative Medicine · 2017 · 37 citations
    20. Murine skin-derived multipotent papillary dermal fibroblast progenitors show germline potential in vitro Stem Cell Research & Therapy · 2023 · 4 citations
    21. Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins Stem cells · 2010 · 106 citations
    22. Biocomposite nanofiber matrices to support ECM remodeling by human dermal progenitors and enhanced wound closure Scientific Reports · 2017 · 87 citations
    23. PI3K/Akt signaling pathway is essential for de novo hair follicle regeneration Stem Cell Research & Therapy · 2020 · 30 citations
    24. Novel in vitro culture condition improves the stemness of human dermal stem/progenitor cells Molecules and Cells · 2013 · 18 citations
    25. SKPing a Hurdle: Sox2 and Adult Dermal Stem Cells Cell stem cell · 2009 · 11 citations
    26. Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice Inflammation and Regeneration · 2023 · 7 citations
    27. Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson–Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies Cells · 2023 · 4 citations
    28. Mechanical engineering of hair follicle regeneration by in situ bioprinting Biomaterials advances · 2022 · 1 citations
    29. Dermal Papilla Cells: From Basic Research to Translational Applications Biology · 2024
    30. Cells, growth factors and biomaterials used in tissue engineering for hair follicles regeneration Regenerative Therapy · 2022