research Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments
The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
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research Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis
The research suggests new treatments for skin cancer could target specific cell growth pathways.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Vitamin D Metabolism and Function in the Skin
Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology
Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair
Fat cells in the skin help start healing and form important repair cells after injury.
research Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Skin Connective Tissue and Aging
Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
research Reversing Wrinkled Skin and Hair Loss in Mice by Restoring Mitochondrial Function
Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
research MicroRNA/mRNA Regulatory Networks in the Control of Skin Development and Regeneration
MicroRNAs are crucial for controlling skin development and healing by regulating genes.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Skin and Hair: Models for Exploring Organ Regeneration
Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
research Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research Stem Cells in Dermatology and Anti-Aging Care of the Skin
Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
research Long-Term Time-Lapse Multimodal Intravital Imaging of Regeneration and Bone Marrow-Derived Cell Dynamics in Skin
The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
research HGF/SF Increases Number of Skin Melanocytes but Does Not Alter Quality or Quantity of Follicular Melanogenesis
HGF/SF increases skin melanocytes but doesn't change melanin type or amount.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Mesothelial Stem Cells and Stromal Vascular Fraction for Skin Rejuvenation
Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Epigenetic Regulations on Skin Wound Healing: Implications from Current Research
Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.
research Stem Cells as a Target for the Delivery of Active Molecules to Skin by Topical Administration
Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
research Multi-Scale Spatial Mapping of Cell Populations Across Anatomical Sites in Healthy Human Skin and Basal Cell Carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.