research Signal Integrator Function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
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research IPSC-Based Approach for Human Hair Follicle Regeneration
The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research Cells, Growth Factors and Biomaterials Used in Tissue Engineering for Hair Follicles Regeneration
Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
research Stimulation of Hair Growth by Small Molecules That Activate Autophagy
Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
research Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in Alzheimer's Disease and Rosacea
Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.
research Cell Therapy for Androgenetic Alopecia: Elixir or Trick?
Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.
research Aesthetic Surgery Applications for Adipose-Derived Stem Cells
Adipose-derived stem cells show promise for cosmetic treatments but need more research.
research Deferasirox, an Oral Iron Chelator, Prevents Hepatocarcinogenesis and Adverse Effects of Sorafenib
Deferasirox combined with sorafenib reduces liver cancer risk and lessens treatment side effects.
research Treatment of Scleroderma-Related Microstomia Using Hyaluronic Acid: An Interventional Study
Hyaluronic acid injections can improve mouth opening and quality of life in scleroderma patients.
research Birt-Hogg-Dubé Syndrome: From Gene Discovery to Molecularly Targeted Therapies
New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
research Disruption of Tubular Flcn Expression as a Mouse Model for Renal Tumor Induction
Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.
research Problems in Evaluating Chronic Toxicity of Contraceptive Steroids in Dogs
High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.
research Let-7b Promotes Alpaca Hair Growth via Transcriptional Repression of TGFβR I
Let-7b helps alpaca hair grow by reducing TGFβR I protein.
research Directed Elimination of Senescent Cells by Inhibition of BCL-W and BCL-XL
Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
research Orchestration of Mesenchymal Stem/Stromal Cells and Inflammation During Wound Healing
Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
research Melatonin Regulates the Periodic Growth of Secondary Hair Follicles Through the Nuclear Receptor RORα
Melatonin helps hair grow by activating the RORα receptor in goats.
research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock
BMAL1 and Period1 genes can influence human hair growth.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Molecular Targeted Agents and Biologic Therapies for Non-Small Cell Lung Cancer
New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
research A Hairy Situation: PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research Cellular Senescence and Aging in Myotonic Dystrophy
Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.
research Life Sciences Discovery And Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research A Novel Connexin 26 Mutation in a Patient Diagnosed with Keratitis–Ichthyosis–Deafness Syndrome
A new mutation in the Connexin 26 gene was found in a patient with KID syndrome, expanding the known disorders linked to this gene.
research Germline Mutation in ATR in Autosomal-Dominant Oropharyngeal Cancer Syndrome
A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.
research Small Molecule Wnt Pathway Modulators from Natural Sources: History, State of the Art and Perspectives
Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
research Comparison of the Acute Ultraviolet Photoresponse in Congenic Albino Hairless C57BL/6J Mice Relative to Outbred SKH1 Hairless Mice
B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
research Keratinic Amyloid Deposition in Canine Hair Follicle Tumors
Some canine hair follicle tumors contain amyloid deposits, with a protein called CK5 involved in their formation.
research DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression
The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
research The Effect of Cilostazol on Hair Growth: A Novel Therapeutic Option for the Treatment of Hair Loss
Cilostazol may help hair grow and could be a new treatment for hair loss.