7 citations,
April 2014 in “Cell biology international” Melatonin treatment helps improve skin health in postmenopausal rats.
2 citations,
November 2017 in “PloS one” Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
4 citations,
November 2022 in “Nutrients” Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
April 2018 in “Journal of Investigative Dermatology” Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.
135 citations,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
41 citations,
May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
1 citations,
May 2022 in “Frontiers in medicine” Metformin helps improve skin regeneration by increasing the growth of skin stem cells.
September 2023 in “Clinical anatomy” Forehead creases are formed by a tight connection between the skin and muscle through dense fibers, with changes in skin thickness and fewer skin appendages near the creases.
January 2015 in “Springer eBooks” Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
150 citations,
April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
44 citations,
October 2011 in “Gynecological Endocrinology” Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
20 citations,
January 2013 in “Plastic & Reconstructive Surgery” The new device safely and effectively rejuvenates skin, making it thicker and healthier.
18 citations,
August 2017 in “PLOS ONE” Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.
2 citations,
December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
November 2022 in “PubMed” Deep dermal tissue dislocation injury in pigs leads to thicker fibrotic tissue and increased type III collagen, affecting skin repair.
187 citations,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
20 citations,
May 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
67 citations,
January 2007 in “Climacteric” Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.
April 2024 in “Current research in nutrition and food science” Taking an amino acid supplement improved skin, hair, and nail health in women.
April 2011 in “한국생물공학회 학술대회” Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.
149 citations,
September 2017 in “Pharmaceutics” Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
26 citations,
April 2011 in “Skin Research and Technology” In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.
15 citations,
February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.
11 citations,
January 2017 in “Oxidative medicine and cellular longevity” Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
9 citations,
January 2016 in “Skin Pharmacology and Physiology” The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
8 citations,
April 2023 in “Advanced materials” Using blood-based implants improves skin healing and reduces scarring.
7 citations,
June 2012 in “Journal of dairy science” Bovine milk fats applied to mouse skin can promote hair growth similar to known hair growth treatments.
4 citations,
June 2022 in “Clinical, cosmetic and investigational dermatology” The new SFS Scale predicts hair transplant difficulty using hair and skin types, with thick skin and coily hair being hardest to work with.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.