46 citations
,
October 2025 in “Journal of Nanobiotechnology” This review examines the potential of plant-derived exosome-like nanovesicles in dermatology, highlighting their bioactive properties and discussing challenges to their clinical application, but does not provide new clinical results.
39 citations
,
August 2022 in “Cell Death and Disease” This study found that a dopamine-methacrylated hyaluronic acid hydrogel enhances the efficacy of adipose-derived stem cells in promoting skin regeneration, potentially involving the Notch signaling pathway.
27 citations
,
September 2009 in “British journal of nursing” This article discusses the role of emollient therapy in managing atopic eczema and other dry skin conditions and reports no new clinical findings.
7 citations
,
May 2025 in “Stem Cell Research & Therapy” This review compiles EV proteomics data and reports that while MSC-derived EVs show promise in skin therapeutics, variability in protein cargo highlights the need for standardized methodologies in understanding process impacts.
3 citations
,
February 2025 in “Frontiers in Cell and Developmental Biology” Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.
December 2025 in “Journal of Education Health and Sport” This study reports that LED phototherapy is gaining popularity as a safe and effective non-invasive method for treating various skin conditions, enhancing skin rejuvenation, wound healing, and inflammation modulation, and is increasingly integrated into clinical protocols for conditions like acne vulgaris and signs of aging.
138 citations
,
May 2000 in “Maturitas” This review discusses the effects of estrogen on skin and reports no new clinical results; it highlights estrogen's potential benefits on skin thickness, collagen quality, and hair follicle life cycle.
35 citations
,
October 2003 in “Dermatologic clinics” This article discusses the lack of national credentialing for laser therapy practitioners and emphasizes the need for rigorous self-assessment and expertise, particularly when treating patients with darker skin, without presenting new research results.
19 citations
,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” This article reviews the cutaneous reactions and characteristic skin changes associated with chemotherapy, radiation therapy, and new targeted cancer treatments, reporting no new clinical results.
8 citations
,
January 2022 in “Burns and trauma” This review discusses the role of extracellular vesicles from specific skin cells in wound healing, emphasizing their potential in regenerative medicine and reporting no new experimental results.
3 citations
,
November 2023 in “Pediatric Transplantation” This study reported that among five children and adolescents who developed new-onset atopic dermatitis after allogeneic hematopoietic stem cell transplantation, topical therapy and skin care improved their skin condition and atopic dermatitis severity scores, potentially reducing the need for excessive immunosuppressive therapy.
2 citations
,
December 2019 in “Electronic Journal of General Medicine” This study found that combining microfocused ultrasound with autologous blood cell factors significantly improved skin rejuvenation compared to using microfocused ultrasound alone.
1 citations
,
May 2024 in “International journal of medicine and psychology.” In this study, researchers found that using electromagnetic radiation in the EHF range enhanced the engraftment of skin flaps in rats by improving microcirculation and reducing necrosis, with greater effects observed when paired with systemic ozone therapy.
1 citations
,
January 2019 in “Journal of Nuclear Technologyin Applied Science (JNTAS) (Print)” This study found that low-level laser therapy accelerates skin regeneration in gamma-irradiated mice and enhances the biostimulatory effect on hair follicles.
June 2024 in “Regenerative Therapy” This review highlights the potential of exosomes as a novel therapeutic approach for skin diseases and aging, due to their stability, transportability, and ability to carry various bioactive compounds to target cells.
This study aimed to investigate the effects of antioxidant therapy on skin aging in MetS patients in Latvia but provides no new findings on its effectiveness.
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
Stem cell therapies show promise for healing skin wounds but need more testing.
27 citations
,
May 2024 in “Clinical and Translational Medicine” This review discusses the origin, characteristics, and therapeutic potential of melanocyte stem cells in skin pigmentation disorders and reports no clinical results.
27 citations
,
March 2006 in “Journal of cosmetic dermatology” This review examines the effects of menopause on skin aging and suggests hormone replacement therapy may improve some symptoms, without providing new clinical findings.
26 citations
,
January 2024 in “Gels” This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.
11 citations
,
January 2013 in “Veterinary dermatology” This study found that a bulge stem cell-enriched population from canine hair follicles successfully formed interfollicular epidermis in vitro within two weeks, suggesting potential for regenerative canine skin therapies.
7 citations
,
June 2022 in “Frontiers in Medicine” This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.
6 citations
,
March 2022 in “International journal of molecular sciences” This review explores the detrimental effects of sunlight on the skin’s circadian rhythm and photodamage, noting the potential of natural cosmeceuticals to influence this rhythm, but reports no new results.
6 citations
,
September 2019 in “Skin pharmacology and physiology” This study found that RCS-01 cell therapy for aged skin was well tolerated and associated with increased gene expression related to extracellular matrix homeostasis, suggesting potential skin improvement.
February 2026 in “American Journal of Clinical Dermatology” This source discusses how radiotherapy-induced skin fibrosis, a chronic side effect affecting cancer survivors' quality of life, is driven by ongoing inflammation and fibroblast activity, and emphasizes the need for comprehensive dermatologic management and better diagnostic tools.
December 2022 in “Medical lasers” This study reviews the mechanism and potential treatment roles of low-level laser therapy for immune-mediated skin diseases, reporting no new clinical results.
November 2022 in “Journal of Investigative Dermatology” This study found that using a home-use LED mask with specific wavelengths improved signs of skin aging in both ex-vivo and clinical settings.
January 2017 in “Elsevier eBooks” This article reviews skin toxicities caused by radiation in metastatic cancer patients and discusses preventive measures, highlighting that current interventions lack robust supporting data.
2 citations
,
November 2025 in “Cells” This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.