202 citations,
June 2005 in “Aaps Pharmscitech” Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
153 citations,
October 2012 in “Skin Pharmacology and Physiology” Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
86 citations,
October 2017 in “Translational pediatrics” Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.
86 citations,
April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
83 citations,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
74 citations,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Minoxidil foam enters hair follicles and skin for hair growth.
73 citations,
July 1956 in “Journal of Investigative Dermatology” Adult human skin can grow new fine hair follicles after a deep exfoliation treatment.
66 citations,
August 2001 in “Experimental Dermatology” Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.
65 citations,
January 2017 in “Postępy Dermatologii i Alergologii” High-frequency ultrasonography is a useful but underused tool in dermatology for assessing skin cancers, monitoring diseases, and evaluating treatments.
64 citations,
April 2005 in “Journal of Investigative Dermatology” Topical oligonucleotide therapy targets hair follicles effectively.
57 citations,
August 1997 in “Microscopy Research and Technique” New molecules involved in skin and hair growth were identified, improving understanding and future treatments.
55 citations,
January 2020 in “Advances in experimental medicine and biology” Vitamin D and its receptor may help prevent skin cancer.
38 citations,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
27 citations,
August 2014 in “Wiley interdisciplinary reviews. Developmental biology” The skin and thymus develop similarly to protect and support immunity.
22 citations,
April 2000 in “International Journal of Dermatology” A 78-year-old farmer with lung disease had skin lesions from a fungal infection that healed completely with medication.
21 citations,
June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
17 citations,
February 2015 in “Cell Death and Disease” Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
16 citations,
August 2014 in “Colloids and surfaces. B, Biointerfaces” Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.
15 citations,
July 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” Fluorescence can effectively measure acne treatment progress.
14 citations,
June 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
14 citations,
June 2020 in “BMC genomics” The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.
14 citations,
February 2020 in “Scientific reports” Telocytes in the scalp may help with skin regeneration and maintenance.
13 citations,
October 2021 in “Anais Brasileiros de Dermatologia” Dermoscopy is effective for diagnosing various skin infestations and infections.
13 citations,
August 2019 in “Biological & Pharmaceutical Bulletin” Certain flavonoids help grow back colored hair after skin injury.
13 citations,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
11 citations,
April 2013 in “Homo” Darker skin in 10-year-old girls may be an early sign of puberty.
5 citations,
January 2021 in “Frontiers in cell and developmental biology” Skin cysts might help advance stem cell treatments to repair skin.
4 citations,
January 2018 in “Cosmetics” Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.
4 citations,
January 2013 in “Humana Press eBooks” Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.