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    Did you mean Skin Cell Differentiation?
    Glossary Skin Cell Differentiation

    process where skin stem cells become specialized functional cells

    Skin cell differentiation is the process by which unspecialized cells in the skin, known as stem cells, develop into specialized cells with specific functions, such as keratinocytes, melanocytes, or fibroblasts. This process is crucial for maintaining healthy skin, enabling it to perform various roles like protection, pigmentation, and wound healing.

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    1. The Role of ATP-dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity Stem cell biology and regenerative medicine · 2018
    2. CLK1 and its Effects on Skin Stem Cell Differentiation Digital WPI · 2010 · 1 citations
    3. 1α,25-Dihydroxyvitamin D3 accelerates skin wound re-epithelialization by promoting epidermal stem cell proliferation and differentiation through PI3K activation: an in vitro and in vivo study Brazilian Journal of Medical and Biological Research · 2025 · 2 citations
    4. Phospholipase C 1 is required for skin stem cell lineage commitment The EMBO Journal · 2003 · 101 citations
    5. Fatty acid oxidation fuels mitochondrial respiration to drive epidermal stem cell fate and differentiation Nature Communications · 2026
    6. Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling PLOS genetics · 2019 · 19 citations
    7. The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells International Journal of Molecular Sciences · 2020 · 3 citations
    8. Abstract C4: Sp2: A regulator of stem cell differentiation and tumorigenesis Cancer Research · 2009
    9. CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance 2019 · 11 citations
    10. Applications of Human Pluripotent Stem Cell–Derived Skin Organoids in Dermatology 2023 · 1 citations
    11. Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties Nature cell biology · 2017 · 143 citations
    12. Stem Cell-Derived and Plant-Derived Exosomes: Promising Therapeutics for Skin Healing and Regeneration Molecular and Cellular Probes · 2026
    13. Retinoic acids shift skin stem cell fate Journal of Investigative Dermatology · 2026
    14. Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance 2016 · 26 citations
    15. Pgc-1α controls epidermal stem cell fate and skin repair by sustaining NAD+ homeostasis during aging Molecular Metabolism · 2022 · 22 citations
    16. 1358 PRC1 fine-tunes gene repression and activation to safeguard skin epithelium development and stem cell specification Journal of Investigative Dermatology · 2018 · 1 citations
    17. A New Horizon in Facial Plastic Surgery: Skin Tissue-Engineering and Stem Cell Therapy—Reality or Dream? The American Journal of Cosmetic Surgery · 2014 · 2 citations
    18. Cloning and induced differentiation of skin stem cells in vitro 2010
    19. Mechanotransductive Differentiation of Hair Follicle Stem Cells Derived from Aged Eyelid Skin into Corneal Endothelial-Like Cells Stem Cell Reviews and Reports · 2021 · 9 citations
    20. Histone H3 K4/9/27 Trimethylation Levels Affect Wound Healing and Stem Cell Dynamics in Adult Skin Stem Cell Reports · 2019 · 26 citations
    21. Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation Frontiers in Cell and Developmental Biology · 2026
    22. Hair follicle differentiation‐specific keratin expression in human basal cell carcinoma Clinical and Experimental Dermatology · 2019 · 45 citations
    23. Function of KLF4 in Stem Cell Biology InTech eBooks · 2013 · 5 citations
    24. 1365 Elf5, a novel regulator of skin stem/progenitor cells fate during skin development? 2023
    25. A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis Cell stem cell · 2021
    26. Human skin stem cells and the ageing process Experimental gerontology · 2008 · 143 citations
    27. Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny during Cutaneous Wound Repair 2018 · 46 citations
    28. Stem Cells in the Skin Springer eBooks · 2012
    29. Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation Frontiers in Cell and Developmental Biology · 2020 · 18 citations
    30. Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles In vitro cellular & developmental biology. Animal · 2008 · 34 citations