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The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.

Hair transplant was successful on a bald area after skin graft surgery.

Artificial hair fibers help treat scalp scars with few complications and a 20% yearly fiber fall rate.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Hair follicle regeneration needs special conditions and young cells.

The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Condensed nanofat with fat grafts effectively improves atrophic facial scars.

Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.

PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

Macrophages are essential for successful skin growth in reconstructive surgery.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Nonablative radiofrequency treatments, especially microneedle and fractional types, can improve acne scars by 25%–75% after 3-4 sessions, with full results in 3 months and some side effects.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.